Protein Alignment NitFhit and Vnn1

DIOPT Version :10

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001020794.1
• Gene: Vnn1 / 29142
• RGDID: 1310075
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 443
• Identity: 86/443 - (19%)
• Similarity: 151/443 - (34%)
• Gaps: 173/443 - (39%)

  Fly    42 STSDKAANLSQVIELVD----RAKSQNACMLFLPE----------------------------CC 74
            |.|:..|.::|.::|::    .|..|.|.::..||                            .|
  Rat    47 SHSEALALMNQNLDLLEGAILSAAKQGAHIIVTPEDGIYGVQFTRDTIYPYLEDIPDPQVNWIPC 111

  Fly    75 DFVGESRTQTIELSEGLDGELMAQYRELAKCNKIWISLGGVHERNDQK---------------IF 124
            |  ...|..:..:.|.|..        |||.|.|::    |....|:|               .:
  Rat   112 D--NPERFGSTPVQERLSC--------LAKNNSIYV----VANMGDKKPCNTSDSHCPPDGRFQY 162

  Fly   125 NAHVLLNEKGELAAVYRKLHMFDVTTKEVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFA 189
            |..|:.:.:|:|.|.|.|.::|....:.....|.:.||        ..||.|:.|:..|:|:.|.
  Rat   163 NTDVVFDSRGKLVARYHKQNLFMGEEQFNAPPEPEVVT--------FDTPFGKFGIFTCFDILFH 219

  Fly   190 EPAV-LLRKLGANLLTYPSAFTYATGKAHW-EILLRARAIETQC---------FVVAAAQI---- 239
            :||| |:.:...:.:.:|:|         | ::|....|||...         |:.|...|
  Rat   220 DPAVTLVTEFQVDTILFPTA---------WMDVLPHLAAIEFHSAWAIGMGVNFLAANLHIPLRR 275

  Fly   240 -------------GWHNQKRQSWGHSMIV--------SP--W----GNVLADCSEQE-------- 269
                         .:|..::...|..::.        ||  |    .:|.|..:|:|
  Rat   276 MTGSGIYAPDSPRAFHYDRKTQEGKLLLAQLDSHPSHSPVNWTSYASSVEAPPTEKEEFRSFVFF 340

  Fly   270 -----LDIGTAEVDLSVLQS------LYQTMPCFEHRRNDIYALTAYNLRSKEPTQDRPFATNIV 323
                 :::.....:.:|.|:      .||..   |.|.:::|||.|::            ..:.|
  Rat   341 DEFTFVELKGITGNYTVCQNDLCCHLSYQMS---EKRADEVYALGAFD------------GLHTV 390

  Fly   324 DKRTIFYESEHCFAFTNLRCVVKGHVLVSTKRVTPRLCG--LDCAEMA-DMFT 373
            :.:   |..:.|             :|:..|....|.||  :|.|... :||:
  Rat   391 EGQ---YHLQIC-------------ILLKCKTTNLRTCGSSVDTASTRFEMFS 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	69/361 (19%)
		FHIT	317..436	CDD:238606	12/60 (20%)
Vnn1	NP_001020794.1	biotinidase_like	27..324	CDD:143591	60/307 (20%)
		Vanin_C	338..484	CDD:465946	22/121 (18%)