DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and Nit2

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	XP_038944121.1	Gene:	Nit2 / 288174	RGDID:	1310494	Length:	360	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	99/280 - (35%)
Similarity:	154/280 - (55%)	Gaps:	11/280 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTI-ELSEGLDGELMAQ 98
            :|:.|::.:|.|:.|:::...||..|..|.|.::.||||  |.....|... |.:|.:.||...:
  Rat    90 LALIQLQVSSIKSDNITRACSLVREAAKQGANIVSLPEC--FNSPYGTNYFPEYAEKIPGESTKK 152

  Fly    99 YRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTK-EVRLRESDTVT 162
            ..|:||.|.|::..|.:.|.:|.|::|...:....|.|...:||:|:||:... ::..:||.|::
  Rat   153 LSEVAKENSIYLIGGSIPEEDDGKLYNTCAVFGPDGNLLVKHRKIHLFDIDVPGKITFQESKTLS 217

  Fly   163 PGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRARAI 227
            ||.... ...||..::||.||||:||||.|.:..:.|..||.||.||...||.||||:|.||||:
  Rat   218 PGDSFS-TFDTPYCRVGLGICYDMRFAELAQIYARRGCQLLVYPGAFNMTTGPAHWELLQRARAV 281

  Fly   228 ETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCF 292
            :.|.:|..|:..........:||||.:|.|||.||.....:| .|..:::||..|..:.|.:|..
  Rat   282 DNQVYVATASPARDEKASYVAWGHSTVVDPWGQVLTKAGTEE-TILYSDIDLKKLSEIRQQIPIL 345

  Fly   293 EHRRNDIYALTAYNLRSKEP 312
            :.:|.|:     |::.||:|
  Rat   346 KQKRADL-----YSVESKKP 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	93/262 (35%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
Nit2	XP_038944121.1	nit	89..349	CDD:143596	93/262 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820