Protein Alignment NitFhit and Vnn3

DIOPT Version :10

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_036109.3
• Gene: Vnn3 / 26464
• MGIID: 1347055
• Length: 500
• Species: Mus musculus
• Alignment Length: 428
• Identity: 85/428 - (19%)
• Similarity: 148/428 - (34%)
• Gaps: 173/428 - (40%)

  Fly   102 LAKCNKIWI--SLGGVHERNDQK---------------IFNAHVLLNEKGELAAVYRKLHMFDVT 149
            |||.|.|:|  ::|      |:|               .:|.:|:.:.||.|.|.|.|.::|:
Mouse   128 LAKENSIYIMANIG------DKKPCNATDPHCPPDGRYQYNTNVVFDSKGRLTARYHKYNLFE-- 184

  Fly   150 TKEVRL---RESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLL---------------- 195
             .|::.   ::|:.||        ..||.|:.|:..|:|:...:|||::
Mouse   185 -PEIQFDFPKDSELVT--------FDTPFGKFGIFTCFDIFSYDPAVVVVKDTQVDSVLLPTAWY 240

  Fly   196 ----------------RKLGANLLTYPSAFT--YATGKA----------HWEI----------LL 222
                            |.:|.|:|...:..|  :.||..          |:::          .|
Mouse   241 NTLPLLSAVPFHSVWARAMGVNVLAANTHNTSMHMTGSGIYSPEAVRVYHYDMETESGQLLLSEL 305

  Fly   223 RARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLAD---------CSEQELDIGTAEVD 278
            |:|..:.    ...|::.|.       .::..|.|:.:..||         .|..:| .|:|. :
Mouse   306 RSRPRQH----ATPAEVNWS-------AYARTVKPFSSGQADFPGKIYFDEFSFTKL-TGSAG-N 357

  Fly   279 LSVLQS---LYQTMPCFEHRRNDIYALTAYN---------------LRSKEPTQDRPFATNIVDK 325
            .:|.|.   .:.|....|.|.:::|.|.|::               |...:.|..|.....:...
Mouse   358 YTVCQKDLCCHLTYKMSESRMDEVYVLGAFDGLHTVEGQYYLQICTLLKCQTTNSRTCGEPVGSA 422

  Fly   326 RTIFYESEHCFAFTNLRCVVKGHVLVSTKRVTPRLCGLDCAEMADMFTTVCLVQRLLEKIYQTTS 390
            .|.|.|......|             .||.|.|::. |..:::|            ||:.|:.:
Mouse   423 FTKFEEFSLSGTF-------------RTKYVFPQIV-LSGSQLA------------LERYYEVS- 460

  Fly   391 ATVTVQDG---AQAGQTVPHV-------HFHIMPRRLG 418
                 :||   ::.|..:|.:       .|...|.|||
Mouse   461 -----RDGRLRSRGGAPLPILVMALYGRVFERDPPRLG 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	56/279 (20%)
		FHIT	317..436	CDD:238606	22/112 (20%)
Vnn3	NP_036109.3	biotinidase_like	26..329	CDD:143591	45/228 (20%)
		Vanin_C	337..488	CDD:465946	33/184 (18%)