DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and SPAC26A3.11

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_594154.1	Gene:	SPAC26A3.11 / 2542673	PomBaseID:	SPAC26A3.11	Length:	322	Species:	Schizosaccharomyces pombe

Alignment Length:	292	Identity:	96/292 - (32%)
Similarity:	157/292 - (53%)	Gaps:	30/292 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IAVGQMRSTSDKAANLSQV-IELVDRAKSQNACMLFLPEC-------------CDFVGESRTQTI 85
            |.:.|:.:|.||:.||... :::::.||: .:.::.|||.             .:.:.||.....
pombe    46 IGLVQLANTKDKSENLQLARLKVLEAAKN-GSNVIVLPEIFNSPYGTGYFNQYAEPIEESSPSYQ 109

  Fly    86 ELSEGLDGELMAQYRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTT 150
            .||            .:||..|.::..|.:.||.|.|::|..::.:..|:|.||:||:|:||:..
pombe   110 ALS------------SMAKDTKTYLFGGSIPERKDGKLYNTAMVFDPSGKLIAVHRKIHLFDIDI 162

  Fly   151 K-EVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATG 214
            . .|..||||:::||..:.. |.|..|:.||.||||:||.|.|::..:.|.:::.||.||..:||
pombe   163 PGGVSFRESDSLSPGDAMTM-VDTEYGKFGLGICYDIRFPELAMIAARNGCSVMIYPGAFNLSTG 226

  Fly   215 KAHWEILLRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDL 279
            ..|||:|.||||::.:.||...|.....|....|||||.:|.|:|.|:|...|:. .|..|::|.
pombe   227 PLHWELLARARAVDNEMFVACCAPARDMNADYHSWGHSTVVDPFGKVIATTDEKP-SIVYADIDP 290

  Fly   280 SVLQSLYQTMPCFEHRRNDIYALTAYNLRSKE 311
            ||:.:...::|.:..||.|:|:.....|:.:|
pombe   291 SVMSTARNSVPIYTQRRFDVYSEVLPALKKEE 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	90/275 (33%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
SPAC26A3.11	NP_594154.1	nit	45..307	CDD:143596	90/275 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810