DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and SPBC651.02

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_595500.1	Gene:	SPBC651.02 / 2541127	PomBaseID:	SPBC651.02	Length:	276	Species:	Schizosaccharomyces pombe

Alignment Length:	272	Identity:	111/272 - (40%)
Similarity:	169/272 - (62%)	Gaps:	10/272 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 AVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTIELSEGLD-GELMAQY 99
            ||.|:.|:.....||:...||:.:|.::.|..:|.||..||:..:..:.|||:...| .:.:...
pombe     5 AVAQLNSSGSILKNLAICKELISQAAAKGAKCIFFPEASDFIAHNSDEAIELTNHPDCSKFIRDV 69

  Fly   100 RELAKCNKIWISLGGVHE--RNDQKIFNAHVLLNE-KGELAAVYRKLHMFDVTTKE-VRLRESDT 160
            ||.|..:.|:::: .|||  :...|:.|:.:.:.. .||:.:.|.|.|:|||..|. ..|:||:|
pombe    70 RESATKHSIFVNI-CVHEPSKVKNKLLNSSLFIEPLHGEIISRYSKAHLFDVEIKNGPTLKESNT 133

  Fly   161 VTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRAR 225
            ...|..:..|..||:|::|..||:|:||.|.|:.||.:||:::|||||||..||.||||:|||||
pombe   134 TLRGEAILPPCKTPLGKVGSAICFDIRFPEQAIKLRNMGAHIITYPSAFTEKTGAAHWEVLLRAR 198

  Fly   226 AIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGT--AEVDLSVLQSLYQT 288
            |:::||:|:|.||.|.||:||.|:||||||.|||.|:|..|:.....|.  |::||:::..:...
pombe   199 ALDSQCYVIAPAQGGKHNEKRASYGHSMIVDPWGTVIAQYSDISSPNGLIFADLDLNLVDHVRTY 263

  Fly   289 MPCFEHRRNDIY 300
            :|..  ||||:|
pombe   264 IPLL--RRNDLY 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	106/266 (40%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
SPBC651.02	NP_595500.1	nit	3..269	CDD:143596	106/266 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	191	1.000	Domainoid score	I722
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1009
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004252
OrthoInspector	1	1.000	-	-		oto101663
orthoMCL	1	0.900	-	-		OOG6_103694
Panther	1	1.100	-	-	LDO	PTHR23088
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R813
SonicParanoid	1	1.000	-	-		X3511
TreeFam	1	0.960	-	-
	12	11.850