DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and SPCC965.09

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_588519.1	Gene:	SPCC965.09 / 2539328	PomBaseID:	SPCC965.09	Length:	272	Species:	Schizosaccharomyces pombe

Alignment Length:	289	Identity:	86/289 - (29%)
Similarity:	137/289 - (47%)	Gaps:	46/289 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ATIAVGQMR-STSDKAANL----SQVIELVDRAKSQNACMLFLPEC------CDFVGESRTQTIE 86
            |.||..||. ...|...||    |.|.|:::...|.|  ::..||.      |   |.:.||..|
pombe     3 ANIACVQMAPKVCDVKHNLQKMSSYVHEVMESNPSTN--LILFPELITSGYEC---GNTFTQIAE 62

  Fly    87 LS-EGLDGELMAQYRELAKCNKIWISLGGVHERNDQK---IFNAHVLLNEKGELAAVYRKLHMFD 147
            :: ||...:.|:........|.|:    |..|:.:::   |:|:.:.:.|.|.|..||||:|:||
pombe    63 IAGEGPSFKTMSNLAAKYHVNIIY----GFPEKEEKQSNIIYNSCIYITENGNLGGVYRKVHLFD 123

  Fly   148 VTTKEVRLRESDTVTPGYCLERPV-STPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAF-- 209
            ...|..: :.||.         |: .|..|::|:.||:|..|.|.|.:....||:||...:.:
pombe   124 TERKHFK-KGSDF---------PIFETSFGKLGVMICWDTAFPEVARIHALNGADLLVVATNWEN 178

  Fly   210 TYATGKAHWEILLRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGT 274
            .|:.   .|:::.:|||.|....:|||.::| .::|...:|||.|:.|.|.|:....|::..:.:
pombe   179 PYSD---DWDLVTKARAFENCIPLVAANRVG-TDEKLSFFGHSKIIGPTGKVIKALDEEKEGVIS 239

  Fly   275 AEVDL---SVLQSLYQTMPCFEHRRNDIY 300
            ..|||   ..|:..|.|.  ||.|..|:|
pombe   240 YTVDLDDAKPLRKNYYTF--FEDRMPDLY 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	82/282 (29%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
SPCC965.09	NP_588519.1	nitrilase	5..261	CDD:143587	82/280 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810