DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and Hint3

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001094295.1	Gene:	Hint3 / 246769	RGDID:	621603	Length:	175	Species:	Rattus norvegicus

Alignment Length:	132	Identity:	27/132 - (20%)
Similarity:	54/132 - (40%)	Gaps:	17/132 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 TQDRPFATNIV----------DKRTIFYESEHCFAFTNLRCVVKGHVLVSTKRVTPRLCGL--DC 365
            ::.|.:.:|.|          :...::.|::....|.:::.....|.||..|:.......|  |.
  Rat    32 SESRDYDSNCVFCRVAAGQEPETELLYCENKDLVCFKDIKPAALHHYLVVPKKHIGSCKDLNKDH 96

  Fly   366 AEMADMFTTVCLVQRLLEKIYQTTSATVTVQDGAQAGQTVPHVHFHIM-PRRLGDFGHNDQIYVK 429
            .||.:...||  .:.:||:...|....|.:........:|.|:|.|:: |.:  :||...::..:
  Rat    97 IEMVESMVTV--GKTILERNNFTDFTDVRMGFHVPPFCSVSHLHLHVIAPAK--EFGFLSRVVYR 157

  Fly   430 LD 431
            .|
  Rat   158 RD 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606	26/128 (20%)
Hint3	NP_001094295.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		0/2 (0%)
		aprataxin_related	40..143	CDD:238609	22/104 (21%)
		Histidine triad motif	136..140		2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0537
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810