DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and Vnn1

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_035834.2	Gene:	Vnn1 / 22361	MGIID:	108395	Length:	512	Species:	Mus musculus

Alignment Length:	264	Identity:	64/264 - (24%)
Similarity:	102/264 - (38%)	Gaps:	74/264 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 STSDKAANLSQVIELVD----RAKSQNACMLFLPECCDFVGESRTQTI--ELSEGLD-------- 92
            |.|:..|.::|.::|::    .|..|.|.::..||...:.......||  .|.|..|
Mouse    47 SHSEALALMNQNLDLLEGAIVSAAKQGAHIIVTPEDGIYGVRFTRDTIYPYLEEIPDPQVNWIPC 111

  Fly    93 ------GELMAQYRE--LAKCNKIWISLGGVHERNDQK---------------IFNAHVLLNEKG 134
                  |....|.|.  |||.|.|::    |....|:|               .:|..|:.:.:|
Mouse   112 DNPKRFGSTPVQERLSCLAKNNSIYV----VANMGDKKPCNTSDSHCPPDGRFQYNTDVVFDSQG 172

  Fly   135 ELAAVYRKLHMFDVTTKEVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAV-LLRKL 198
            :|.|.|.|.::|....:.....|.:.||        ..||.|:.|:..|:|:.|.:||| |:.:.
Mouse   173 KLVARYHKQNIFMGEDQFNVPMEPEFVT--------FDTPFGKFGVFTCFDILFHDPAVTLVTEF 229

  Fly   199 GANLLTYPSAFTYATGKAHW-EILLRARAIETQC---------FVVAAAQIGWHNQKRQSWGHSM 253
            ..:.:.:|:|         | ::|....|||...         |:.|    ..||..|:..| |.
Mouse   230 QVDTILFPTA---------WMDVLPHLAAIEFHSAWAMGMGVNFLAA----NLHNPSRRMTG-SG 280

  Fly   254 IVSP 257
            |.:|
Mouse   281 IYAP 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	64/264 (24%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
Vnn1	NP_035834.2	biotinidase_like	27..324	CDD:143591	64/264 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900