Protein Alignment NitFhit and nft-1

DIOPT Version :9

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_499556.1
• Gene: nft-1 / 176628
• WormBaseID: WBGene00003594
• Length: 440
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 211/428 - (49%)
• Similarity: 278/428 - (64%)
• Gaps: 10/428 - (2%)

  Fly    35 IAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTIELSEGLDGELMAQY 99
            |||.||.|.:|...|......:::||..:...|:|||||.||:|.::.:.|:|:...|.|.|.:|
 Worm    17 IAVCQMTSDNDLEKNFQAAKNMIERAGEKKCEMVFLPECFDFIGLNKNEQIDLAMATDCEYMEKY 81

  Fly   100 RELAKCNKIWISLGGVHERNDQKI---FNAHVLLNEKGELAAVYRKLHMFDVTTK-EVRLRESDT 160
            ||||:.:.||:||||:|.::....   :|.|::::..|...|.|.|||:||:... :|||.||:.
 Worm    82 RELARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHLFDLEIPGKVRLMESEF 146

  Fly   161 VTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRAR 225
            ...|..:..||.||:|::||.||||:||.|.::..||.||.||::|||||..||.||||.|||||
 Worm   147 SKAGTEMIPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLSFPSAFTLNTGLAHWETLLRAR 211

  Fly   226 AIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMP 290
            |||.||:||||||.|.||.||||:||||:|.|||.|:|.|||: :|:..||:|||.:.:|.:..|
 Worm   212 AIENQCYVVAAAQTGAHNPKRQSYGHSMVVDPWGAVVAQCSER-VDMCFAEIDLSYVDTLREMQP 275

  Fly   291 CFEHRRNDIYALTAYNLRSKEPTQDRPFATNIVDKRTIFYESEHCFAFTNLRCVVKGHVLVSTKR 355
            .|.|||:|:|.| ..|.:|.| |....||...:....|||.:.|.|.|.||:.|..||||||.||
 Worm   276 VFSHRRSDLYTL-HINEKSSE-TGGLKFARFNIPADHIFYSTPHSFVFVNLKPVTDGHVLVSPKR 338

  Fly   356 VTPRLCGLDCAEMADMFTTVCLVQRLLEKIYQTTSATVTVQDGAQAGQTVPHVHFHIMPRRLGDF 420
            |.|||..|..||.||:|.....||.:|||.:..||.|:.||||..|||||||||.||:|||.|||
 Worm   339 VVPRLTDLTDAETADLFIVAKKVQAMLEKHHNVTSTTICVQDGKDAGQTVPHVHIHILPRRAGDF 403

  Fly   421 GHNDQIYVKL--DERAEEKPPRTIEERIEEAQIYRKFL 456
            |.| :||.||  .::..|:.||:.|:..|||.:||..:
 Worm   404 GDN-EIYQKLASHDKEPERKPRSNEQMAEEAVVYRNLM 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	129/264 (49%)
		FHIT	317..436	CDD:238606	64/120 (53%)
nft-1	NP_499556.1	nit	17..281	CDD:143596	129/264 (49%)
		FHIT	300..418	CDD:238606	64/118 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166129
Domainoid	1	1.000	243	1.000	Domainoid score	I1228
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76584
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1151
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29090
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	1	1.000	-	-		FOG0004252
OrthoInspector	1	1.000	-	-		oto20100
orthoMCL	1	0.900	-	-		OOG6_103694
Panther	1	1.100	-	-	LDO	PTHR23088
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R813
SonicParanoid	1	1.000	-	-		X3511
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840