DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NitFhit and upb-1

DIOPT Version :9

Sequence 1:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_495261.1	Gene:	upb-1 / 174040	WormBaseID:	WBGene00017440	Length:	387	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	75/324 - (23%)
Similarity:	121/324 - (37%)	Gaps:	51/324 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QLRRMSVQKRKDQS--------ATIAVGQMRSTSDKAANLSQVIE-----LVDRAKSQNACMLFL 70
            ||....|..:|:|:        |.|.....|.|:|........|.     :::.|.|..|.::.|
Worm    55 QLSGYIVDAQKEQTRAPRLVRVAAIQNKIHRPTTDSVVEQRDAIHQRVGAMIEAAASAGANVIGL 119

  Fly    71 PECCD----FVGESRTQTIELSEGL-DGELMAQYRELAKCNKIWISLGGVHERNDQK---IFNAH 127
            .|...    |....|....|.:|.: .|.......:||..:.| :.:..:.||:::|   |:|..
Worm   120 QEAWTMPFAFCTRERLPWTEFAESVYTGPTTQFLSKLAVKHDI-VIISPILERDEEKDDVIWNTA 183

  Fly   128 VLLNEKGELAAVYRKLHMFDVTTKEVRLRESDTVTPGYCLERPVSTPV-----GQIGLQICYDLR 187
            |:::..|.:....||.|:         .|..|.....|.:|..:..||     |:||:.|||...
Worm   184 VVISHTGRVIGRSRKNHI---------PRVGDFNESTYYMESTLGHPVFETKYGRIGINICYGRH 239

  Fly   188 FAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRARAIETQCFVVAAAQIGW----------- 241
            ..:..::....||.::..|||...|..:..|.|..|..||....|.|...::|.
Worm   240 HPQNWMMYALNGAEIIFNPSATVGALSEPLWGIEARNAAIANHVFTVGINRVGTEVFPNEFTSGN 304

  Fly   242 ----HNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCFEHRRNDIYA 301
                |......:|.|.|.:|.|:.....|.....:..||:||::.:............|.|:||
Worm   305 GQPAHKDFGHFYGSSYIAAPDGSRTPALSRVREGVLIAELDLNLCRQCKDAWGFRMTNRLDMYA 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	65/294 (22%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
upb-1	NP_495261.1	ML_beta-AS	11..373	CDD:143611	75/324 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810