Protein Alignment NitFhit and Fhit

DIOPT Version :10

• Sequence 1: NP_525122.1
• Gene: NitFhit / 38029
• FlyBaseID: FBgn0024945
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001295214.1
• Gene: Fhit / 14198
• MGIID: 1277947
• Length: 213
• Species: Mus musculus
• Alignment Length: 239
• Identity: 77/239 - (32%)
• Similarity: 106/239 - (44%)
• Gaps: 52/239 - (21%)

  Fly   230 QC--------FVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLY 286
            ||        |.:....|||.|.|          .||.|:|...|.:.|.:.     |...:|.|
Mouse    11 QCNQMQDVGAFKIVFYLIGWTNLK----------VPWDNLLGHTSARTLHLA-----LRTPRSFY 60

  Fly   287 QTMPCFEHRRNDIYALTAYNLRSKEPTQDRPFATNIVDKRTIFYESEHCFAFTNLRCVVKGHVLV 351
                |                    .|....|..:::....:|.::|..||..|.:.||.|||||
Mouse    61 ----C--------------------ETMSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLV 101

  Fly   352 STKRVTPRLCGLDCAEMADMFTTVCLVQRLLEKIYQTTSATVTVQDGAQAGQTVPHVHFHIMPRR 416
            ...|...|...|...|:||:|.....|..::||.:|.||.|.::|||.:|||||.|||.|::||:
Mouse   102 CPLRPVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRK 166

  Fly   417 LGDFGHNDQIYVKLD--ERAEEKPP---RTIEERIEEAQIYRKF 455
            .|||..||.||.:|.  :|.||..|   |:.:|...||:..|.:
Mouse   167 AGDFPRNDNIYDELQKHDREEEDSPAFWRSEKEMAAEAEALRVY 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NitFhit	NP_525122.1	nit	34..296	CDD:143596	18/73 (25%)
		FHIT	317..436	CDD:238606	50/120 (42%)
Fhit	NP_001295214.1	FHIT	68..187	CDD:238606	50/118 (42%)