DRSC/TRiP Functional Genomics Resources

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Protein Alignment NitFhit and HINT3

DIOPT Version :9

Sequence 1:NP_525122.1 Gene:NitFhit / 38029 FlyBaseID:FBgn0024945 Length:460 Species:Drosophila melanogaster
Sequence 2:NP_612638.3 Gene:HINT3 / 135114 HGNCID:18468 Length:182 Species:Homo sapiens


Alignment Length:85 Identity:19/85 - (22%)
Similarity:35/85 - (41%) Gaps:4/85 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   331 ESEHCFAFTNLRCVVKGHVLVSTKR--VTPRLCGLDCAEMADMFTTVCLVQRLLEKIYQTTSATV 393
            |:|....|.:::.....|.||..|:  ...|....|..|:.:...||  .:.:||:...|....|
Human    67 ENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTV--GKTILERNNFTDFTNV 129

  Fly   394 TVQDGAQAGQTVPHVHFHIM 413
            .:........::.|:|.|::
Human   130 RMGFHMPPFCSISHLHLHVL 149

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NitFhitNP_525122.1 nit 34..296 CDD:143596
FHIT 317..436 CDD:238606 19/85 (22%)
HINT3NP_612638.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..42
aprataxin_related 47..150 CDD:238609 19/85 (22%)
Histidine triad motif 143..147 2/3 (67%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0537
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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