Protein Alignment mri and BTBD10

DIOPT Version :9

• Sequence 1: NP_612008.1
• Gene: mri / 38028
• FlyBaseID: FBgn0035107
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: XP_016873894.1
• Gene: BTBD10 / 84280
• HGNCID: 21445
• Length: 518
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 216/455 - (47%)
• Similarity: 282/455 - (61%)
• Gaps: 75/455 - (16%)

  Fly     6 SLNSSSSNISSKAPLAQKQDTYSSDSSEEVLE----------TAEERRRRILKERSRLN------ 54
            ||:.:|..........:..|. |.|||.|..|          |:..|:..:.:|:...:
Human    58 SLHGASGGHERSRDRRRSSDR-SRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSP 121

  Fly    55 RPQH-----NMSGGGAVPKHDIKSPCGASPSCQATGSGM---------GRLPLPPERITMLVDGV 105
            |||.     ::|..|...::..:|  .:..||:..|..:         .|.....||:|::||..
Human   122 RPQKASPNGSISSAGNSSRNSSQS--SSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNT 184

  Fly   106 RFTVEQSLLTAHPTTMLGTMFGSG--FQFAHTNERGEYDVADGISHLVFRAILEYYKSGVIRCPP 168
            ||.|:.|:.||.|.||||.|||||  ..|...||:|||:||:||...||||||:|||:|:||||.
Human   185 RFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPD 249

  Fly   169 TVSVPELKEACDYLLIPFDATTVRCQNLRGLLHELSNEGARQQFELFLEDLILPLMVASAQRGDR 233
            .:|:|||:||||||.|.|:.:|::|::|..|:|||||:|||:|||.:||::||||||||||.|:|
Human   250 GISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGER 314

  Fly   234 ECHVVVLLEDDMVEWDEEFPPQMGEEYCQT----------------------------------- 263
            |||:|||.:||:|:||||:||||||||.|.
Human   315 ECHIVVLTDDDVVDWDEEYPPQMGEEYSQIHLLREITQPEREKARNVHQSNSLKFSAHLEDSTCF 379

  Fly   264 VHSTAMHRFFKYIENRDVAKQVMKDRGLKKIRCGIEGYPTHKEKIRRRPGGRAEVIYSYVQRPFI 328
            ::||.::|||||||||||||.|:|:|||||||.|||||||:|||:::|||||.||||:|||||||
Human   380 IYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFI 444

  Fly   329 HMSWEKEEAKSRHVDFQCVKSKSVTNLAEANADPPLELDASGNPIP-----PIAVANPHPNNAEL 388
            .|||||||.||||||||||||||:||||.|.||.|.:.....:|.|     .|...:|...|::|
Human   445 RMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDL 509

  Fly   389  388
            Human   510  509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mri	NP_612008.1	BTB	98..199	CDD:197585	58/102 (57%)
		BTB_3	128..357	CDD:292636	163/265 (62%)
BTBD10	XP_016873894.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141944
Domainoid	1	1.000	278	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3840
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	409	1.000	Inparanoid score	I1879
Isobase	1	0.950	-	0	Normalized mean entropy	S3037
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191593at33208
OrthoFinder	1	1.000	-	-		FOG0003068
OrthoInspector	1	1.000	-	-		otm40639
orthoMCL	1	0.900	-	-		OOG6_105618
Panther	1	1.100	-	-	O	PTHR21637
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4069
SonicParanoid	1	1.000	-	-		X2047
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740