DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mri and Btbd10

DIOPT Version :9

Sequence 1:	NP_612008.1	Gene:	mri / 38028	FlyBaseID:	FBgn0035107	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_006230095.1	Gene:	Btbd10 / 308890	RGDID:	1306301	Length:	483	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	217/415 - (52%)
Similarity:	281/415 - (67%)	Gaps:	44/415 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SLNSSSSNISSKAPLAQKQDTYSSDSSEEVLE----------TAEERRRRILKERSRLN------ 54
            ||:.:|..........:..|. |.|||.|..|          |:..|:..|.:|:...:
  Rat    58 SLHGASGGHERSRDRRRSSDR-SRDSSHERAESQLTPCIRNVTSPTRQHHIEREKDHSSSRPSSP 121

  Fly    55 RPQH-----NMSGGGAVPKHDIKSPCGASPSCQATGSGM---------GRLPLPPERITMLVDGV 105
            |||.     ::|..|...::..:|  .:..||:|:|..:         .|.....||:|::||..
  Rat   122 RPQRASPNGSISSAGNSSRNSSQS--SSDGSCKASGEMVFVYENAKEGARSVRTSERVTLIVDNT 184

  Fly   106 RFTVEQSLLTAHPTTMLGTMFGSG--FQFAHTNERGEYDVADGISHLVFRAILEYYKSGVIRCPP 168
            ||.|:.|:.||.|.||||.|||||  ..|...||:|||:||:||...||||||:|||:|:||||.
  Rat   185 RFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPD 249

  Fly   169 TVSVPELKEACDYLLIPFDATTVRCQNLRGLLHELSNEGARQQFELFLEDLILPLMVASAQRGDR 233
            .:|:|||:||||||.|.|:.:|::|::|..|:|||||:|||:|||.:||::||||||||||.|:|
  Rat   250 GISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGER 314

  Fly   234 ECHVVVLLEDDMVEWDEEFPPQMGEEYCQTVHSTAMHRFFKYIENRDVAKQVMKDRGLKKIRCGI 298
            |||:|||.:||:|:||||:||||||||.|.::||.::|||||||||||||.|:|:|||||||.||
  Rat   315 ECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGI 379

  Fly   299 EGYPTHKEKIRRRPGGRAEVIYSYVQRPFIHMSWEKEEAKSRHVDFQCVKSKSVTNLAEANADPP 363
            |||||:|||:::|||||.||||:|||||||.|||||||.||||||||||||||:||||.|.||.|
  Rat   380 EGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIP 444

  Fly   364 LELDASGNPIPPIAVANPHPNNAEL 388
            .:         .:.|.:|.|...||
  Rat   445 QD---------QLVVMHPTPQVDEL 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mri	NP_612008.1	BTB	98..199	CDD:197585	58/102 (57%)
mri	NP_612008.1	BTB_3	128..357	CDD:292636	163/230 (71%)
Btbd10	XP_006230095.1	BTB_3	209..438	CDD:292636	161/228 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335660
Domainoid	1	1.000	278	1.000	Domainoid score	I1636
eggNOG	1	0.900	-	-		E1_KOG3840
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	411	1.000	Inparanoid score	I1801
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191593at33208
OrthoFinder	1	1.000	-	-		FOG0003068
OrthoInspector	1	1.000	-	-		otm44778
orthoMCL	1	0.900	-	-		OOG6_105618
Panther	1	1.100	-	-	O	PTHR21637
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2047
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.800