Protein Alignment mri and KCTD20

DIOPT Version :10

• Sequence 1: NP_612008.1
• Gene: mri / 38028
• FlyBaseID: FBgn0035107
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_775833.2
• Gene: KCTD20 / 222658
• HGNCID: 21052
• Length: 419
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 188/337 - (55%)
• Similarity: 239/337 - (70%)
• Gaps: 29/337 - (8%)

  Fly    70 DIKSPCGASPSCQ--------------ATGSGMGRLPLPPERITMLVDGVRFTVEQSLLTAHPTT 120
            |||..|..|.:.:              :.|.|.......||::|:||||.||.|...:.||||.|
Human    77 DIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDT 141

  Fly   121 MLGTMFGSG--FQFAHTNERGEYDVADGISHLVFRAILEYYKSGVIRCPPTVSVPELKEACDYLL 183
            |||.|||.|  :.|...||:|||::|:|||..|||.:|:|||:|:|.||..:|:|:|::.||||.
Human   142 MLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLC 206

  Fly   184 IPFDATTVRCQNLRGLLHELSNEGARQQFELFLEDLILPLMVASAQRGDRECHVVVLLEDDMVEW 248
            |.||..|:|||:|..|||||||:||.:||:.:||:||||:||..|::|:||||:|||.::|.|:|
Human   207 INFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDW 271

  Fly   249 DEEFPPQMGEEYCQTVHSTAMHRFFKYIENRDVAKQVMKDRGLKKIRCGIEGYPTHKEKIRRRPG 313
            ||:.||.|||||.|.::|:.::|||||||||||||.|:|:||||.||.|||||||.||||:||||
Human   272 DEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPG 336

  Fly   314 GRAEVIYSYVQRPFIHMSWEKEEAKSRHVDFQCVKSKSVTNLAEANAD-----------PPL--E 365
            ||:||||:|||||||.|||||||.||||||||||:|||:|||..|..|           ||.  |
Human   337 GRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDE 401

  Fly   366 LDASGNPIPPIA 377
            ||....|:..:|
Human   402 LDRLNAPLSQMA 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mri	NP_612008.1	BTB_3	97..200	CDD:464976	56/104 (54%)
KCTD20	NP_775833.2	BTB_POZ_KCTD20	115..218	CDD:349694	56/102 (55%)
		PH-like	280..>319	CDD:473070	26/38 (68%)