DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rno and AT5G55040

DIOPT Version :9

Sequence 1:	NP_001246528.1	Gene:	rno / 38027	FlyBaseID:	FBgn0035106	Length:	3241	Species:	Drosophila melanogaster
Sequence 2:	NP_001119438.1	Gene:	AT5G55040 / 835595	AraportID:	AT5G55040	Length:	916	Species:	Arabidopsis thaliana

Alignment Length:	1015	Identity:	191/1015 - (18%)
Similarity:	321/1015 - (31%)	Gaps:	300/1015 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   874 VSKRKSSSGSPLKKQSYARSVEQRQKQRQR--RQNEAVAGASATYPDSRSASSSSDGEDERCRNR 936
            ::.|:||| || ::..|    |.|:.||||  |.|       ..:.|........:.|:|:.|.:
plant    18 LAARRSSS-SP-RESGY----ELRRGQRQRNVRYN-------FDFDDYFDEEEEDEVEEEKKRQK 69

  Fly   937 Q-------EPERGARRGPIQSKSVPNRSQASRSKPTTEADVGEGTGASARRKLSTTTRGLAQMDK 994
            :       ...|.....|::|:: ..|..:...:...|.|..|........|.....|.|.:.|:
plant    70 KLKQVLKLNQSRARADPPVKSRA-RVRHASDYEEEDEEDDEAEEEEEEVSEKRQVKKRKLNRQDE 133

  Fly   995 DADESVSSD--------------ESEELLPLRGERQRESTTTSGLATTGSAIGRNLGQHIYSDSE 1045
            :.:|....|              :|||    ..:::|:..:.||          |...|   .||
plant   134 EEEEEEEKDYDVEEEEEEEEGHADSEE----EDDKERKRRSASG----------NQCDH---SSE 181

  Fly  1046 SSSSEQEK----------------------DQEEQATVESNVSDSQNQQTIRTKAA------MKE 1082
            ::....:|                      |.||.......:....:..|:|.|.|      ::|
plant   182 TTPILDKKSLELILDKLQKKDIYGVYAEPVDPEELPDYHDMIEHPMDFSTVRKKLANGSYSTLEE 246

  Fly  1083 FVPGTAATTSSTSQAASSTS----KAKNTREG------------KEGAASIGNSTKTKPNPNAKL 1131
            .........|:..|..||.:    :|:..:|.            |.....:....|.||:.:.|
plant   247 LESDVLLICSNAMQYNSSDTVYYKQARTIQEMGKRKFEKARLKIKRAEKELKTDEKVKPDSSVK- 310

  Fly  1132 YPADLLVVPQRQAAKKASEN---------MRSTNLATTLQPDVSDRVREPDINSISGTAKSKVKD 1187
                      :|..:..|.|         ....|||:.     .....||....|.|..|....|
plant   311 ----------KQVRQPFSRNGLEAVGSDFSSGANLASG-----GASQNEPVSTQIGGHEKHSYTD 360

  Fly  1188 SSSRVSNEADKSSLEKVRPKEHLQKTVGKTSESAPAERGKRGRPPKVPKDARPPSITENDK---- 1248
                |..|.:.|.::.:...|.|....|..        ||.||...|.::.|..:..::|:
plant   361 ----VLFEGNTSLVDSLEKAEDLSSGKGLF--------GKCGRKLSVVEEDRRATYEDSDQQGDR 413

  Fly  1249 -PALPTHTQSKPPSVVATPVSAK-------SNFAVSLVPQRQAAKKAAEQLKSSKPVLESFSTGN 1305
             .::.|..:|:....||..:.|:       :.||.:|.|  .|.|.|:::::.:.|....|..|
plant   414 SESIFTTFESEIKQFVAVGLHAEHAYGRSLARFAATLGP--VAWKIASQRIEQALPADFKFGRG- 475

  Fly  1306 DISDKETVTSATISGSGSSVPAASTPVKPTRRSSIKEAPITPKEPLSGRRKSKEDLLATPIKTTP 1370
            .:.:.|.:.:..:      :....||.:|.     |:|.:..|...:...|:.|.|..||:   |
plant   476 WVGEYEPLPTPVL------LFETCTPKEPP-----KKASVFSKRKSNAATKTNETLFKTPL---P 526

  Fly  1371 LVKRRVVVPNLSSSSSGDSESSSSSSSSGSSSSSGGSDSDSESQASNSENPSSREPPVAPAKVPS 1435
            ..:::...|....:.:....:|..:.|.||.|...       :|..|.::.|..|     .:.||
plant   527 AKEQQGSRPVRDGNHAFPFPASIGALSEGSPSFVA-------TQVGNLKSMSQHE-----YRNPS 579

  Fly  1436 DSSLVPKRSPRKSMDKPSALTIAPASVNVLNIPSTRSRQNSTTKSTKVALQKAVQSVEDDVKCTP 1500
            ....|          ||.  ...|..|. ||:|....:.||   .:...|:.......|.|....
plant   580 QLDFV----------KPQ--NRIPQQVE-LNLPPPAEQTNS---GSGCVLENQSFGKSDTVASYR 628

  Fly  1501 KTNRLQGSMDECGKQVQLEQATKR-----ATRGSKSRP----------------PSPTAKSSPEK 1544
            .::.:..:|.....:....|.|..     ..|..|..|                .|.||.||.:.
plant   629 SSSDMMRNMSSTDSEHYKHQMTTNGIFPGGLRNGKVSPGVNNRMFDLSTDFANQMSRTATSSQQP 693

  Fly  1545 TVSRCKSRAEESPKKVANLEQEISQRKVASGKGTSSLDKLLNKKQQQMNHSAQATPPPI-SPTPP 1608
            ...:.:|..|:     |.:.:..::|.......|             .||.....||.| ||...
plant   694 MRQQSQSHEEQ-----AQIMRNFNERARTQHNST-------------YNHPKADAPPKISSPQSA 740

  Fly  1609 ASETRIVKDQCDLKPDEVSIQQ--INLGADAQPEPDLDPESAAEAGELPMDIDEELTTAPTRTQL 1671
            .||        |.....|:..:  :::||....:...:..|..::.:    |..|....|:|...
plant   741 RSE--------DSGNASVAAARAWMSIGAGGNNKQTFENASNPKSSQ----ISAESLYNPSREHF 793

  Fly  1672 SASASKLADI--------------------------------IDDERPPAAPLPASPTPTPTSND 1704
            ...|.|..|.                                ..:.||...|..|:||
plant   794 HQQAFKPRDAEETQFHPQRNGFPFQTFVHQPVHGMMNGGYQPFQNNRPIVFPQMAAPT------- 851

  Fly  1705 EMSDAGSDLSE-RRRMRWRS--------RRRRRRRSHEPD 1735
                  ||.|. ..:.:||.        ::|:...:..||
plant   852 ------SDFSRFHVQSQWRGGITPQVQLKQRQENFNLPPD 885

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rno	NP_001246528.1	COG5141	250..>664	CDD:227470
		EPL1	<250..288	CDD:287484
		PHD_JADE	314..359	CDD:277048
		ePHD_RNO	367..480	CDD:277177
		TFIIA	2138..>2295	CDD:281188
AT5G55040	NP_001119438.1	Bromodomain	187..283	CDD:99922	15/95 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900