DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rno and SDG16

DIOPT Version :9

Sequence 1:	NP_001246528.1	Gene:	rno / 38027	FlyBaseID:	FBgn0035106	Length:	3241	Species:	Drosophila melanogaster
Sequence 2:	NP_194520.3	Gene:	SDG16 / 828904	AraportID:	AT4G27910	Length:	1027	Species:	Arabidopsis thaliana

Alignment Length:	688	Identity:	166/688 - (24%)
Similarity:	253/688 - (36%)	Gaps:	147/688 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TTAAVAEVTGSGPATGSERVPVLPLCKSKHEEPGAEAGGGGQGRAAAGATSTSKSKS-------- 103
            |..:..|:..:.|..|        |.| ||..|.|.||    ...........|.|.
plant   336 TAVSNQELNNNAPRQG--------LLK-KHRNPLACAG----CETVISFEMAKKMKDLIPGDQLL 387

  Fly   104 ----TKLAKSASKC----KSQGASSSSSWQARSVADIKMSSIYNRSSTEAPAELYRKDLISAMKL 160
                ::|.||...|    |.:....:.||.......:::.:..::.|.....:|...|..    .
plant   388 CKPCSRLTKSKHICGICKKIRNHLDNKSWVRCDGCKVRIHAECDQISDRHLKDLRETDYY----C 448

  Fly   161 PDSEPLANYEYLIVTDPWKQEWE----KGVQVPVNPDSLPEPCVYVLPEPVVSPAHDFKL----- 216
            |......|::   ::|..||..:    ||....|.||.:...|..|  |.|..|.....:
plant   449 PTCRAKFNFD---LSDSEKQNSKSKVAKGDGQMVLPDKVIVVCAGV--EGVYFPRLHLVVCKCGS 508

  Fly   217 --PKNRYL----RIT--KDEHYSPDLHYLTNVVALAENTCAYDIDPIDEAWL----RLY-NSDRA 268
              ||.:.|    |.|  |.:::...:...::.:||             |.|:    .|: |:..|
plant   509 CGPKKKALSEWERHTGSKSKNWKTSVKVKSSKLAL-------------EDWMMNLAELHANATAA 560

  Fly   269 QCGAFPINATQFERVIEELEVRCWEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCD 333
            :....|....:.:|::..|. ..:|.:......|.           |.|||..:..:.|:::.|:
plant   561 KVPKRPSIKQRKQRLLAFLS-ETYEPVNAKWTTER-----------CAVCRWVEDWDYNKIIICN 613

  Fly   334 NCNICVHQACYGITAIPS-GQWLCRTCSM-GIKPDCVLCPNKGGAMKSNKSGKHWAHVSCALWIP 396
            .|.|.|||.|||...:.. ..|:|:.|.. .||.:|.|||.||||:|.......|.||:||.:.|
plant   614 RCQIAVHQECYGARHVRDFTSWVCKACERPDIKRECCLCPVKGGALKPTDVETLWVHVTCAWFQP 678

  Fly   397 EVSIGCVDRMEPITKISSIPQSRWSLICVLCRKRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAI 461
            ||.....::|||...|.|||.:.:..|||:|::..|||.||.  .|.|.||..||.:.|..|...
plant   679 EVCFASEEKMEPAVGILSIPSTNFVKICVICKQIHGSCTQCC--KCSTYYHAMCASRAGYRMELH 741

  Fly   462 IEEGNAEDGVKLRSYCQKHSMSKGKKENAGSHGGGSASVASAMQKANRYGSGAGGGA-------- 518
            ..|.|.:...|:.|||..|...............|:.|..|.:|...:      ||:
plant   742 CLEKNGQQITKMVSYCAYHRAPNPDNVLIIQTPSGAFSAKSLVQNKKK------GGSRLISLIRE 800

  Fly   519 DDGNNACGTTGEDP---------RRRKNHRK-------TELTSEERNQARA-----QRLQEVEAE 562
            ||...|..|...||         :|:.|.:|       ...|...|:.|.|     ...:.|..|
plant   801 DDEAPAENTITCDPFSAARCRVFKRKINSKKRIEEEAIPHHTRGPRHHASAAIQTLNTFRHVPEE 865

  Fly   563 FDKHVNFNDISCHLFDVDDDAIVAIYNYWKLKRKSRHNRELIPPKS-EDVEMIARKQEQQDMENH 626
            .....:|.:...||...:.|.:.       ..|...|...|...:: ::.||:...:.:|...:
plant   866 PKSFSSFRERLHHLQRTEMDRVC-------FGRSGIHGWGLFARRNIQEGEMVLEYRGEQVRGS- 922

  Fly   627 KLVVHLRQ-DLERVRNLCYMVSRREKLSRSLFKLREQV 663
              :..||: ...||...||           |||:.|:|
plant   923 --IADLREARYRRVGKDCY-----------LFKISEEV 947

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rno	NP_001246528.1	COG5141	250..>664	CDD:227470	119/452 (26%)
		EPL1	<250..288	CDD:287484	7/42 (17%)
		PHD_JADE	314..359	CDD:277048	16/45 (36%)
		ePHD_RNO	367..480	CDD:277177	47/112 (42%)
		TFIIA	2138..>2295	CDD:281188
SDG16	NP_194520.3	WHSC1_related	205..308	CDD:99899
		PHD_SF	401..451	CDD:304600	8/53 (15%)
		PHD_ATX3_4_5_like	594..640	CDD:276970	16/56 (29%)
		ePHD_ATX3_4_5_like	649..760	CDD:277133	47/112 (42%)
		SET	886..1004	CDD:214614	17/83 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13793
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010