DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rno and Kdm4d

DIOPT Version :9

Sequence 1:	NP_001246528.1	Gene:	rno / 38027	FlyBaseID:	FBgn0035106	Length:	3241	Species:	Drosophila melanogaster
Sequence 2:	NP_001073180.1	Gene:	Kdm4d / 689582	RGDID:	1591045	Length:	510	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	52/244 - (21%)
Similarity:	83/244 - (34%)	Gaps:	56/244 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  2681 SKTSTSDARSQIKLKIKSPMAYPEHYNAMTNSSSLTLTSTLVQSSNVVQTT---VSTSTVVSASS 2742
            |:.|..:||....:.....:..||.|........    ..:|..:..:..|   ::|..|:.|..
  Rat   305 SQCSCGEARVSFSMDAFVRILQPERYEMWKRGQD----QAVVDHTEAMGPTSQELTTWRVIQAPR 365

  Fly  2743 AVSGNSRRMRKKELLSLYVVQKDNHNDDSSCGLPAASDTLPLENLRKSEEEDELSGGNGTKRFKK 2807
            ...| .:.:|.:::              |.|.||.|:|:....|.:...          |.|...
  Rat   366 KTWG-LKHLRLRQV--------------SRCLLPVATDSNIANNTQMCH----------TSRQAA 405

  Fly  2808 NSSSRELRALDANLALVEEQLLSSGAGACGGGSSGDGRRRSACSSGSNNDNNGKTGAASSAGKRR 2872
            :|...|::..|..:|......||| .|....|..|.|||  .|..|.....||      :..|||
  Rat   406 DSKGDEVQESDPAIAPPYPLGLSS-PGHMSTGKRGLGRR--PCELGVQESTNG------APVKRR 461

  Fly  2873 GRSKTLESSEDDHQAPKLKIKIRGLT---------ANETPSGVSSVDEG 2912
                 |....|| ::|..:::.:.:|         .|..|....:..||
  Rat   462 -----LPEGRDD-RSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEG 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rno	NP_001246528.1	COG5141	250..>664	CDD:227470
		EPL1	<250..288	CDD:287484
		PHD_JADE	314..359	CDD:277048
		ePHD_RNO	367..480	CDD:277177
		TFIIA	2138..>2295	CDD:281188
Kdm4d	NP_001073180.1	JmjN	15..55	CDD:128818
		JmjC	176..292	CDD:202224
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	397..510		31/133 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900