DRSC/TRiP Functional Genomics Resources

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Protein Alignment rno and Brpf1

DIOPT Version :9

Sequence 1:NP_001246528.1 Gene:rno / 38027 FlyBaseID:FBgn0035106 Length:3241 Species:Drosophila melanogaster
Sequence 2:XP_006237117.1 Gene:Brpf1 / 679713 RGDID:1584828 Length:1252 Species:Rattus norvegicus


Alignment Length:1229 Identity:293/1229 - (23%)
Similarity:423/1229 - (34%) Gaps:420/1229 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 QHHQSHH-----PPPQQ-----HQRKDVE--------PQPPPTKRRKGRP-PNGATTAAVAEVTG 56
            ::|..|:     |||||     |::|..:        |.|....:..||. .:.|....:.||..
  Rat    39 EYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDL 103

  Fly    57 SGPATGSERVPVLPLCK--SKHEEPGAEAGGGGQGRAAAGATSTSKSKSTKLAKSASKCKSQGAS 119
            .|..   .|:.:.....  |:.||...||...|..:    ..:.:.:.:.|..|..:|.|.:.: 
  Rat   104 HGRV---HRISIFDNLDVVSEDEEAPEEAPENGSNK----ENTETPAATPKSGKHKNKEKRKDS- 160

  Fly   120 SSSSWQARSVADIKMSSIYNRSSTEAPAELYRKDLISAMKLPDSEPLANYEYLIVTDPWKQEWEK 184
                               |.....|||.       :|.|||:          :|.....|:   
  Rat   161 -------------------NHHHHSAPAS-------AAPKLPE----------VVYRELDQD--- 186

  Fly   185 GVQVPVNPDSLPEPCVYVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNVVALAENTCA 249
                  .||:.|.|..|.                 ||:..:.:|               .:....
  Rat   187 ------TPDAPPRPTSYY-----------------RYIEKSAEE---------------LDEEVE 213

  Fly   250 YDIDPIDEAWLRLYNSDRAQCGAFPINATQFERVIEELEVRCWEQIQVILKLEEG-LGIEFDENV 313
            ||:|..|..||.:.|..|...|..||....||.:::.||...:.:..     .:| .....||:.
  Rat   214 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESH-----NKGDPNALVDEDA 273

  Fly   314 ICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTC--SMGIKPDCVLCPNKGGA 376
            :|.:|...:.:.:|.::|||.||:.|||.|||:..||.||||||.|  |.....||.||||||||
  Rat   274 VCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGA 338

  Fly   377 MKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCRKR-VGSCIQCSVK 440
            .|....|: ||||.||||||||.......:|||..|..||.:||.|.|.:|::| .|:||||...
  Rat   339 FKQTDDGR-WAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKA 402

  Fly   441 PCKTAYHVTCAFQHGL--EMRAIIEEG--NAEDGVKLRSYCQKH------------SMSKGKKEN 489
            .|.||:|||||.|.||  :|..:.|.|  .....|:..:||..|            |.|:|::|.
  Rat   403 NCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEE 467

  Fly   490 AGSHGGG----SASVASA-------MQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKTEL 543
            ......|    |..|..|       |:||.:..:.....|...:..|         ...||.:::
  Rat   468 DEEEDEGKSWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPC---------IPPHRLSKI 523

  Fly   544 TSEERNQARAQRLQEVEAEFDKHVNFNDISCHLFDVDDDAIVAIYNYWKLKRKSRHNRELIP--- 605
            |:....|.::|.:|.                            :::||.|||:||:...|:.   
  Rat   524 TNRLTIQRKSQFMQR----------------------------LHSYWTLKRQSRNGVPLLRRLQ 560

  Fly   606 ---PKSEDVEMIARKQEQQD---MENHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFKLREQVF 664
               ....:.:.:.|..|.::   .|..|....||.||||.|.|..::.:||||.|...|:::...
  Rat   561 THLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAM 625

  Fly   665 YKQLG---VLDEMRLEKQQTKQEQ---QQPVMDLNAVIYANDGPTLYDR---------------- 707
            ..||.   :|....||:.|.|...   .:|| .|:.|...::.|...|.                
  Rat   626 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPV-PLSEVTELDEVPDYLDHIKKPMDFFTMKQNLEA 689

  Fly   708 -----------------------------FYSSV------GG----------------------- 714
                                         ||.:.      ||                       
  Rat   690 YRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHI 754

  Fly   715 ---------------------------QTVPAQYQDLKYILEQLMGKLQSGKQGRGR-------- 744
                                       :.:|.:.| ||.:||:| .::.:.||..||        
  Rat   755 PHNLAGDEVSHHTEDVEEERLVLLENQKHLPVEEQ-LKLLLERL-DEVNASKQSVGRSRRAKMIK 817

  Fly   745 ----------ASQSPNKRKQPAKASPNKKLN----------NGILSS--RTSSPEKTVAG----- 782
                      |.|....|..|.:..|:.:.|          :|...|  ..||.::|..|     
  Rat   818 KEMTALRRKLAHQRETGRDGPERHGPSGRGNLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNM 882

  Fly   783 -----SKVGTTTS--------KVRSPPGKNPTGRRASKSSAAAATSTHNKS-----------QFH 823
                 .:||..||        |...|| |.|  .|..|:..:..|.:|..|           ...
  Rat   883 SSTPAHEVGRRTSVLFSKKNPKTAGPP-KRP--GRPPKNRESQMTPSHGGSPVGPPQLPIMGSLR 944

  Fly   824 SNIRSSTTSHSSSGTISSGNSSS-------ANGTSSSD------------------SSSGSDSGS 863
            ...|..:...|||....|..|:.       |||.||.:                  |||.|:|.|
  Rat   945 QRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSSGNQPVKKSFLVYRNDCNLPRSSSDSESSS 1009

  Fly   864 ESGSSSAGSGVSKRKSSSGSPLKKQSYARSV--EQRQKQRQRRQNEAVA-------GASATYPDS 919
            .|.||:|....|...|..|.  .|.|::|..  |...:.....:|||.:       |.|:.||  
  Rat  1010 SSSSSAASDRTSTTPSKQGR--GKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSSKYP-- 1070

  Fly   920 RSASSSSDGEDERCRNRQEPERGARRGPIQSKSVP---NRSQASRSKPTTEADVGEGTG 975
                              .|:.|......||.:.|   :.|..|||.......:|.|.|
  Rat  1071 ------------------HPKSGVLGTQFQSLASPPAADPSPLSRSCEVVRKSLGRGAG 1111

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rnoNP_001246528.1 COG5141 250..>664 CDD:227470 146/453 (32%)
EPL1 <250..288 CDD:287484 13/37 (35%)
PHD_JADE 314..359 CDD:277048 22/44 (50%)
ePHD_RNO 367..480 CDD:277177 57/117 (49%)
TFIIA 2138..>2295 CDD:281188
Brpf1XP_006237117.1 EPL1 106..254 CDD:287484 44/232 (19%)
PHD_BRPF1 266..327 CDD:277146 26/60 (43%)
ePHD_BRPF1 329..449 CDD:277171 58/120 (48%)
Bromo_brd1_like 631..734 CDD:99944 15/103 (15%)
BR140_related 1121..1236 CDD:99900
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5141
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D566217at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

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