Protein Alignment rno and Kdm4b

DIOPT Version :9

• Sequence 1: NP_001246528.1
• Gene: rno / 38027
• FlyBaseID: FBgn0035106
• Length: 3241
• Species: Drosophila melanogaster
• Sequence 2: NP_001037701.2
• Gene: Kdm4b / 301128
• RGDID: 1588576
• Length: 1099
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 146/628 - (23%)
• Similarity: 214/628 - (34%)
• Gaps: 215/628 - (34%)

  Fly    10 QQHHQSHHPPPQQHQRKDVEPQPPPTKRRKGRPPNGATTAAVAEVTGSGPATGSERVPVLP---- 70
            ::...:..|.|..|:|:.   ||..:|....|.|..||    |.|.|...|.|..|...:|
  Rat   395 RRREPTRRPGPASHRRRS---QPKKSKPEDSRSPGEAT----AGVAGLDEARGCSRRETMPEEEE 452

  Fly    71 ---LCKSK-HEEPGAEAGGGGQGRAAAGATSTSKSKSTKLAKSASKCKSQGASSSSSWQARSVAD 131
               |..|: ||..|.|..|.|:.|       .:|::|.|
  Rat   453 EEELSPSQGHEAEGVEEDGRGKPR-------PTKARSKK-------------------------- 484

  Fly   132 IKMSSIYNRSSTEAPAELYRKDLISAMKLPDSE--------PLANY-----EYLIVTDPWKQEWE 183
             |..|:.:.....||..|:..:  ..::||...        |:|..     ..|.|..|    ..
  Rat   485 -KTPSLLSPPLLSAPPALFPAE--EVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPP----GV 542

  Fly   184 KGVQVPVNPDSLPEPCVYVLP-------------EPVVSP------------------------- 210
            .|.:..|.|..: .|.:||||             .|.::|
  Rat   543 PGEETEVRPRPI-IPMLYVLPRANSSDGDREHAAHPQLAPMELGPEEEDQAQAGDSQGTTSFSKL 606

  Fly   211 --------AHDFKLPKNRY-LRITKDEHYSPDLHY------------------------------ 236
                    .|....|..|. |.:.|.|..|.:..:
  Rat   607 KVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDGSDPEALRSLLSLQWKSKAASFQ 671

  Fly   237 ----LTNVVALAENTCAYDIDPIDEAWLRLYNSDRAQCGAF-PIN-ATQFERVIEELEVRCWEQI 295
                |....||:|..||.                   |..| |.: :.|.||  |.|.......:
  Rat   672 AERKLNAAAALSEPYCAV-------------------CTLFYPYSQSVQTER--EVLATPGDSAV 715

  Fly   296 QVILKLEEGLGIEFDENVICDVCRSPDSEE-----ANE---------MVFCDNCNICVHQACYGI 346
            |...|..:.     ...:|.::|.:...|.     ||.         ::.|.:|.:.||.:|||:
  Rat   716 QPPSKSGQR-----TRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGV 775

  Fly   347 -TAIPSGQWLCRTCSM-GIKPDCVLCPNKGGAMKSNKSGKH-WAHVSCALWIPEVSIGCVDRMEP 408
             ..:....|.|..|:. ....:|.||..:|||::  ::.:| |.||.||:.:|||....|....|
  Rat   776 RPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQ--RTTEHRWIHVICAIAVPEVRFLNVIERNP 838

  Fly   409 ITKISSIPQSRWSLICVLCRKRV----GSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAED 469
            : .:|:||:.||.|.||.||||:    |:|||||.:.|.|::|||||...|:.|       ..:|
  Rat   839 V-DVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLM-------EPDD 895

  Fly   470 GVKLRSY-CQKHSMSKGKKENAGSHGGGSASVASAMQKANRYG 511
            ...:.|. |.||..|     .||.....:.|:...:...||.|
  Rat   896 WPYVVSITCLKHRAS-----GAGGQLLRTVSLGQIVITKNRNG 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rno	NP_001246528.1	COG5141	250..>664	CDD:227470	81/286 (28%)
		EPL1	<250..288	CDD:287484	7/39 (18%)
		PHD_JADE	314..359	CDD:277048	14/59 (24%)
		ePHD_RNO	367..480	CDD:277177	47/118 (40%)
		TFIIA	2138..>2295	CDD:281188
Kdm4b	NP_001037701.2	JmjN	15..56	CDD:128818
		JmjC	176..292	CDD:396791
		AvrE	475..>671	CDD:338078	33/236 (14%)
		PHD_SF	686..789	CDD:419867	26/128 (20%)
		ePHD_JMJD2B	798..907	CDD:277184	47/118 (40%)
		Tudor_JMJD2B_rpt1	920..973	CDD:410535	4/14 (29%)
		Tudor_SF	977..1032	CDD:413384

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810