DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rno and gtf3c5

DIOPT Version :9

Sequence 1:	NP_001246528.1	Gene:	rno / 38027	FlyBaseID:	FBgn0035106	Length:	3241	Species:	Drosophila melanogaster
Sequence 2:	XP_002936239.2	Gene:	gtf3c5 / 100492614	XenbaseID:	XB-GENE-1012275	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	477	Identity:	84/477 - (17%)
Similarity:	144/477 - (30%)	Gaps:	183/477 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly  1976 SGPNSV--ASLTI---KDSPMTA--------NSGSYANSLTNTPNATPTNATMN---NLGYQVNF 2024
            |||::.  .|.|:   :..||..        :.|....:|......:.|.|..:   .|.::.|.
Frog     2 SGPSTAMEGSATVILPRTKPMVCVEYPGLVRDVGKMLRTLGGEEGVSKTYADPSKRLELYFRPND 66

  Fly  2025 P-------NSQPPPTLGLFLEKSPHQKGACPLSSNGGANVGQPAPTPD-FVDLAAAAVKNTLGSF 2081
            |       |..|..|:.|.::|...:|.|        .:.|.|.||.: .:.|....|..|:..|
Frog    67 PYCHPLCGNRFPTTTMILRVKKKVRRKKA--------PDPGAPEPTEEGKISLEIIGVVGTVYKF 123

  Fly  2082 RGAATVPTQSGTGVNAKINDYDESTRMQSPFGGMPWNESDLIAERRSSSPSSVSESNDPPQ---P 2143
            :|               ::|:......|.|.|    |.:.|..:.....|......|....   |
Frog   124 QG---------------MSDFQYLAFKQDPDG----NRTSLYDKVLLCKPEKEDFFNQEIALHIP 169

  Fly  2144 PPVVTATATTARSLAQLESCKNFFNSYPSGNAGPGTAANATAPFNHPPMVNGIDS--IPMFNNTN 2206
            ||:          .::|::|.::|                     :.|.||..:.  :|..:|.|
Frog   170 PPI----------FSRLDNCVDYF---------------------YRPDVNHREGYRLPQVSNDN 203

  Fly  2207 ---------------------TTQHQPTTP----------------AHQQQQQRTPNN------- 2227
                                 ...::|..|                |.::.:|...|.
Frog   204 LIGLSRARRPHNAIFVSFEEAEIPNEPLQPAVKNWTKMCTNPMDKQAEEEMRQLFTNRPIWSRNA 268

  Fly  2228 -QYNGTIYPQLAGIMHP------QTTP-------------TEPPSSLYG------NGGVGGAVQS 2266
             :.|.:::|....::.|      .|.|             ..|.:.:|.      ..||......
Frog   269 IKANISVHPDKLKLLLPIVAYYMLTGPWRSLWVRFGYDPRKNPEAKIYQVLDFRIRCGVKYGYAP 333

  Fly  2267 TTLPPPAQVNQYPGTPYSATTLGMISVQQPALSTVPVQ---------TATTPN------NPFTLT 2316
            ..:|..|:.:.|   .||..    |::::||...|.||         ::.||.      |.:.|.
Frog   334 NDMPVKAKRSTY---NYSLP----ITLKKPAPQVVSVQDLKQGLAAPSSNTPGGTKPGFNKYKLK 391

  Fly  2317 SPI----DGKMPTYPAQLLSSC 2334
            ..|    :|.:|.|.......|
Frog   392 ESIYIFQEGNLPPYRQMFYQLC 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rno	NP_001246528.1	COG5141	250..>664	CDD:227470
		EPL1	<250..288	CDD:287484
		PHD_JADE	314..359	CDD:277048
		ePHD_RNO	367..480	CDD:277177
		TFIIA	2138..>2295	CDD:281188	33/231 (14%)
gtf3c5	XP_002936239.2	Tau95_N	25..132	CDD:375251	24/129 (19%)
gtf3c5	XP_002936239.2	Tau95	168..322	CDD:370643	24/184 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900