Protein Alignment rno and brpf3b

DIOPT Version :10

• Sequence 1: NP_612007.2
• Gene: rno / 38027
• FlyBaseID: FBgn0035106
• Length: 3241
• Species: Drosophila melanogaster
• Sequence 2: XP_005166793.1
• Gene: brpf3b / 100003354
• ZFINID: ZDB-GENE-081104-468
• Length: 1222
• Species: Danio rerio
• Alignment Length: 1390
• Identity: 318/1390 - (22%)
• Similarity: 485/1390 - (34%)
• Gaps: 429/1390 - (30%)

  Fly    80 GAEAGGGGQGRAAAGATSTSKSKSTKLAKSASKCKSQGASSSSSWQARSVADIKMSSIYNRSSTE 144
            ||::.....|.||...:........:|..|.::      .:.:..||:.:.::.:....:|.|..
Zfish    12 GAQSDASDTGTAAVEDSQPRSPSPYRLKVSPTR------ETLTYAQAQKIVEVDLDGRLHRISIF 70

  Fly   145 APAELYRKDLISAMKLPDSEPLANYE-------YLIVTDPWKQEWEKGVQVPV------------ 190
            .|..:..:|.::|..:  :|..:|.|       ..:|:.|.:....:|.:..|
Zfish    71 DPLVVITEDEMTAQDI--AECNSNKENSEQTSVSTVVSSPRRSVANRGKKKDVKQLSSSQNHCSN 133

  Fly   191 -------------NPDSLPEPCV--YVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNV 240
                         :..:||:|..  :...|||.:|..    |...|..|.|... .||
Zfish   134 SHGQSQTQSSGNSHHGTLPKPTFKEHEFYEPVEAPPR----PSAYYRYIDKSSE-DPD------- 186

  Fly   241 VALAENTCAYDIDPIDEAWLRLYNSDRAQCGAFPINATQFERVIEE------LEVRCWEQIQVIL 299
                 ....||:|..|.|||.|.|..|...|...|:...||.:|:.      ||.|.....|.::
Zfish   187 -----TDAEYDMDEEDVAWLELVNEKRDSDGQPHISPDTFELLIDRLEKESFLESRSQASSQSVI 246

  Fly   300 KLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTC--SMG 362
                      ||:..|.||...:...:|.::|||.||:.|||.|||:..||.||||||.|  |..
Zfish   247 ----------DEDAFCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPS 301

  Fly   363 IKPDCVLCPNKGGAMKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLC 427
            ...|||||||:|||.|....|: ||||.||:|||||.......:|||..:.:||.:||.|.|.||
Zfish   302 RPVDCVLCPNRGGAFKQTSDGR-WAHVVCAIWIPEVCFANTVFLEPIEGVDNIPPARWKLTCYLC 365

  Fly   428 R-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAEDG----VKLRSYCQKHS--MSKG 485
            : |..|:.|||....|.||:|||||.:.||.|:.........:|    ||..::|:.||  ::..
Zfish   366 KQKGCGASIQCHKANCYTAFHVTCAQRAGLFMKIDPVRETTVNGTTFSVKKTAFCEAHSPAVNGS 430

  Fly   486 KKENAGSHGGGSASVASAMQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKTELTSEERN- 549
            ..|..|....|.        :||| |..|.....:.....|:...|.::.:...|.|..|::..
Zfish   431 DDEETGGRVLGC--------RANR-GRSAYMQTPELKKQKGSNKVDSKQPQKKGKKEEVSKKTTT 486

  Fly   550 ------QARAQRLQEVEAEFDKHVNFNDISCHLFDVDDDAIVAIYNYWKLKRKSRHNRELIPPKS 608
                  :..||||.::..:.            :....:..:..::|||.|||:||:...||....
Zfish   487 LLVTVPEIPAQRLNKISKDV------------IIQKKNQFMQRLHNYWLLKRQSRNGVPLIRRLH 539

  Fly   609 EDVEMIARKQEQQD--------MENHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFKLREQVFY 665
            ..::. .|..||.:        .|..|....||.||||.|.|..::.:||||.|...|:.:.|..
Zfish   540 SHLQG-QRSAEQAEPDEKLNAVREELKYWQKLRHDLERARLLIELIRKREKLKREQVKIHQAVTE 603

  Fly   666 KQLG---VLDEMRLEKQQTKQEQQ---QPV---------------MDL----------------- 692
            .||.   ||....||:.|.|...:   |||               ||.
Zfish   604 HQLTPVLVLLSSTLEQLQEKDTAKIFAQPVNLKEVPDYLEFITHPMDFSTMQSKLEAHKYRSVTD 668

  Fly   693 ----------NAVIYANDGPTLYDRFYSS------VGG---QTVPAQYQDLKYILEQLMGKLQSG 738
                      |.::| |...|:   ||.:      :||   :....|.|:..:.|:..|
Zfish   669 LEADFNLMISNCLLY-NAKDTV---FYQAAIRLRDLGGAILRHAQRQAQNTGFDLDTGM------ 723

  Fly   739 KQGRGRASQSPNKRKQ--------PAKASPNKKLNNGILSSRTSSPEKTVAGSKVGTTTSKVRSP 795
                 ..::||||...        .....|:.:|:      .|:..:......|:...||
Zfish   724 -----HLAESPNKNDYYRCTFEDVDTLLDPDNRLH------MTTENQLRELLEKLDVVTS----- 772

  Fly   796 PGKNPTGRRASKSSAAAATSTH------NKSQFHSNIRSSTTSHSSSGTISSGNSSSANGTSSSD 854
                      .:||.|......      ||.:|..|::               ||...||    |
Zfish   773 ----------MRSSGARTRRVRLLRREINKVRFKQNLK---------------NSHMLNG----D 808

  Fly   855 SSSGSDSGSESGSSSAGSGVSKRKSSSGSPLKKQSYARSVEQRQKQRQRRQNEAVAGASATYPDS 919
            .....|...|.....|                                               |.
Zfish   809 LKEDDDEDDEDKEMDA-----------------------------------------------DH 826

  Fly   920 RSASSSSDGEDERCRNRQEPERGARRGPIQSKSVPNRSQASRSKPTTEADVGEGTGASA---RRK 981
            ..:|||||.:|  |::...|    ...|......|......:..||......:...:|.   |.|
Zfish   827 NLSSSSSDKDD--CKSTPPP----MLEPTGLALSPPPGDTPQEPPTLRPMTSDPRTSSCPPKRLK 885

  Fly   982 LSTTTRGLAQMDKDADESVSSDESEELLPLRGERQRESTTTSGLATTGS-------AIGRNLGQH 1039
            |::..:   ::|.|.....|..:.|:..|       |....:||::|.|       .:||.....
Zfish   886 LNSERQ---ELDSDPTPMNSCTKLEDAPP-------EIKLFNGLSSTESPSRPNTGGVGRRTSVL 940

  Fly  1040 IYSDSESSSSEQEKDQEEQATVESNVSDSQNQQTIRTKAAMKEFVPGTAATTSSTSQAASSTSKA 1104
            .......:..::|:|.:.|   ..|..|....:|....|.:|         |.:|:|...||
Zfish   941 FKKAKNGAKLQRERDNQMQ---NGNREDGDAARTHNCTATVK---------TETTAQPKPST--- 990

  Fly  1105 KNTREGKEGAASIGNSTKTKPNPNAKLYPADLLVVPQRQAAK--KASENMRSTNLATTLQPDVSD 1167
                                |.|         :.||.:|..:  ..|.....|....||:|.:::
Zfish   991 --------------------PPP---------ISVPAKQQTRSHSCSPERERTPPRLTLEPALTN 1026

  Fly  1168 RVRE-------------PDINS-ISGTAKSKVKDSSSR------VSNEADKSSLEKVRPKEHLQK 1212
            ..|:             |.:.. ||...||:.|.:.|:      |:.::|.:..:.:
Zfish  1027 GFRKHKDGGSDSECSSSPTLRELISPPKKSRGKPALSKVPFLETVNGDSDYTGTDVL-------- 1083

  Fly  1213 TVGKTSESAPAE---RGKRGRP--------PKVPKDARPPSITENDKPALPTHTQSKPPSVVATP 1266
            :.|.|.|..|.:   ...||.|        |.:|:|    .:..|..| :|.     ||..|
Zfish  1084 SNGDTPEPEPLDLVWAKSRGYPSYPALIIDPDMPQD----GLLHNGVP-IPV-----PPLDV--- 1135

  Fly  1267 VSAKSNFAVSLVPQRQAAKKAAEQL 1291
                    :.|..|||  ::|.|:|
Zfish  1136 --------LRLGEQRQ--EEAGERL 1150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rno	NP_612007.2	COG5141	250..>664	CDD:227470	148/443 (33%)
		ePHD_RNO	367..480	CDD:277177	53/117 (45%)
		PHA03247	<1222..1481	CDD:223021	20/81 (25%)
		Chi1	2171..>2348	CDD:442692
brpf3b	XP_005166793.1	EPL1	63..231	CDD:463128	40/186 (22%)
		COG5141	170..>613	CDD:227470	158/492 (32%)
		PHD_SF	306..423	CDD:473978	53/117 (45%)
		Bromo_brd1_like	608..705	CDD:99944	19/100 (19%)
		PHA03307	841..>1074	CDD:223039	53/290 (18%)
		PWWP_BRPF3	1091..1208	CDD:438986	20/83 (24%)