DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtch and Mtch2

DIOPT Version :9

Sequence 1:	NP_001246525.1	Gene:	Mtch / 38026	FlyBaseID:	FBgn0027786	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001304259.1	Gene:	Mtch2 / 295922	RGDID:	1308080	Length:	314	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	107/277 - (38%)
Similarity:	157/277 - (56%)	Gaps:	11/277 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GVSAALHPFEYSKTLIQLGYEPIAPLPGKSILGKPIMKLPNIFQYAGHIRRIDGFYGCYRGLAPK 90
            |::....|..|.|.|||:||||:.|..|::|.|:.:.:||.:|.||.||..|||..|.:.||.|:
  Rat    13 GLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVYQLPGLFCYAQHIASIDGKRGLFTGLTPR 77

  Fly    91 LVGSLVAMVVSDRVADQL-GLEQPEENKDDSQLSDEELYVQFKKSLK---RDIVLMVSGVVASHP 151
            |...::..||..:|.... ..|:||:.  .|....:|....|.:.:|   |:::...:..:.:||
  Rat    78 LCSGVLGTVVHGKVLQYYQECEKPEDL--GSANVQKEYPSSFDRVIKETTREMIARSAATLITHP 140

  Fly   152 FHVISLRMMAQFVGRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNK 216
            ||||:||.|.||:|||:.|..:..|:..|::.|||.||||||:|:||||:..|.|.:|..|::|.
  Rat   141 FHVITLRSMVQFIGRESKYCGLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINT 205

  Fly   217 YIIKDKLG-----RQYNSGFTQFAVSSLLYPLQVVSTCSAVSGSRLMAAQPPIMPAYRNWVDCWN 276
            |.:...:.     :.|:...|.|..|.|.||..:||...||:...|....||..|.|.:|:|||.
  Rat   206 YALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGSPPYSPIYTSWIDCWC 270

  Fly   277 DLQVRGELKRGSSLFWR 293
            .||..|.:.||:|||:|
  Rat   271 MLQKAGNMSRGNSLFFR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtch	NP_001246525.1	Mito_carr	142..222	CDD:278578	37/79 (47%)
Mtch2	NP_001304259.1	Mito_carr	128..>192	CDD:278578	31/63 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349364
Domainoid	1	1.000	78	1.000	Domainoid score	I8578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8645
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3743
OMA	1	1.010	-	-		QHG49093
OrthoDB	1	1.010	-	-		D1439019at2759
OrthoFinder	1	1.000	-	-		FOG0004199
OrthoInspector	1	1.000	-	-		mtm9121
orthoMCL	1	0.900	-	-		OOG6_107248
Panther	1	1.100	-	-	LDO	PTHR10780
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4015
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910