DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13875 and rassf10b

DIOPT Version :9

Sequence 1:	NP_001261185.1	Gene:	CG13875 / 38024	FlyBaseID:	FBgn0035104	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_001921665.1	Gene:	rassf10b / 335170	ZFINID:	ZDB-GENE-030131-7110	Length:	448	Species:	Danio rerio

Alignment Length:	456	Identity:	114/456 - (25%)
Similarity:	197/456 - (43%)	Gaps:	80/456 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LPSQSESFSIWVNGEEHWISGADSSTTCADLICALISYQIDQKHVLSKEEILAPQQFAIVQKQRH 79
            :.::....|:||..||..:||....|||||:|..|:..|..::.|....   :||.:.||:|.|.
Zfish     1 MEAEENKVSVWVCREEKLVSGLSKRTTCADVIRVLLEEQNQEQRVSLPG---SPQSYCIVEKWRG 62

  Fly    80 YEEYLDSSARLLDVITSPHAMPKEEYQLH---LRHLATSS-------------RKQVPTTDKDSG 128
            :|..|.:..::|.:.:   |..:|:..:.   |::.|:.|             .|:.|...|.:.
Zfish    63 FERILPNKTKILRLWS---AWGEEQENVRFVLLKNEASLSSSGPRSAEARVVLSKESPCVYKGTA 124

  Fly   129 -MGSPVDSSRSMRIRRRGKLLSTKTTDNINTKQSKRSRKQQQRNHHLTPNESLLTIILAQDETIL 192
             :...:...:..||.|:    :.:..|.||.|:::.:.|.......:   |:|:.::::||.||.
Zfish   125 RVTMALSHEKQRRIVRK----AFRKLDKINKKRAQAASKDASCMEKM---ETLVHLVISQDHTIR 182

  Fly   193 QQMTMLHEKDRQIFKIEEEKHQVRERELGKNYLLETYLKDL--DEPQEKG--EDLELFEEMTHID 253
            ||:..:.|.||:|.|.|.:.|..|.:..|.||:.:|||.|.  :.|.|..  |.|..|||... .
Zfish   183 QQVQRIKELDREIDKYEAKVHFDRMKMHGINYVQDTYLVDAKNENPDETSPEEALAQFEEYAQ-R 246

  Fly   254 VDRDFGIMSDSTVQTALNSG---TMQDDIRLYWLEKIHE--VNKELQCEEELLLSLHSKVRRHQV 313
            .:....:..:.....||..|   .:|:::...|:::.|:  .||:.:...: ..||.......|.
Zfish   247 CEEVIKLQDELAENEALMEGITTEIQEELNQRWMKRRHQELANKDSESTSD-EASLRVTTLETQA 310

  Fly   314 KRAYQTKSEVLLQIERLDTELATQVADIHHVERKLFTANEQLKAKLAVLECLSREFETTVSGGVQ 378
            .......:||||:.||:.|:|.|.:    ::..:|.|..|.::..|::.|.:         .|.:
Zfish   311 SADPSPDNEVLLEEERIRTQLDTSL----YIGLRLNTDLEAIRNDLSLTEEI---------WGAK 362

  Fly   379 EGDVATGSNASAKVQQSQSDDLQHAGNWLHVVKRLFAADHLNRRLTQQALSEKNL--TDRLIPSK 441
            |.::.               ||....|.|.     |..|...    ...|.|:|.  ||||:|.|
Zfish   363 EKELM---------------DLMEKVNSLD-----FEIDAEG----DAELKEENTGGTDRLVPLK 403

  Fly   442 G 442
            |
Zfish   404 G 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13875	NP_001261185.1	None
rassf10b	XP_001921665.1	RA	7..95	CDD:214612	28/93 (30%)
rassf10b	XP_001921665.1	SMC_N	<82..392	CDD:330553	80/355 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003658
OrthoInspector	1	1.000	-	-		otm26548
orthoMCL	1	0.900	-	-		OOG6_111442
Panther	1	1.100	-	-	O	PTHR15286
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3544
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.910