DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13875 and Ppp1r13b

DIOPT Version :9

Sequence 1:	NP_001261185.1	Gene:	CG13875 / 38024	FlyBaseID:	FBgn0035104	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_038968345.1	Gene:	Ppp1r13b / 314465	RGDID:	1304651	Length:	1220	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	75/379 - (19%)
Similarity:	134/379 - (35%)	Gaps:	126/379 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 KEEYQLHLRHLATSSRKQVPTTDKDSGMGSPVDSSRSMRIRRR-GKLLSTKTTDN---------- 155
            :||.:..|||      :..||...:.|    ...|:..|.:|. ..:...|.|:|
  Rat   170 REEVKFFLRH------EDSPTESSEQG----ARQSQEQRTQRNVMNVPGEKHTENGVGNPRVELT 224

  Fly   156 INTKQSKRSRKQQQRNHHLTPNESLLTIILAQDETILQQMTMLHEKDRQI-FKIEEEKHQVRERE 219
            ::..|...:|:|||                     |..|..||..|:::: |..::|:.|  ::.
  Rat   225 LSELQDMAARQQQQ---------------------IESQQQMLVAKEQRLHFLKQQERRQ--QQS 266

  Fly   220 LGKNYLLETYLKDLDEPQEKGEDLELFEEMTHIDVDRDFGIMSDSTVQTALNSGTMQDDIRLYWL 284
            :.:|..|:. ||:..|.||..                                           |
  Rat   267 ISENEKLQK-LKERVEAQENK-------------------------------------------L 287

  Fly   285 EKIHEVNKELQCEEELLLSLHSKVRRHQVKRAYQTKSEVLLQIERLDTELATQVADIHHVERKLF 349
            :||..:..::...:.:..:|.:::.|... ...:.|.||...|.|:| :|:.|:.|:...:...|
  Rat   288 KKIRAMRGQVDYSKIMNGNLSAEIERFSA-MFQEKKQEVQTAILRVD-QLSQQLEDLKKGKLNGF 350

  Fly   350 TA-NEQLKAKLAV-LECLSREFETTVSGGVQEGDVATGSNASAKVQQSQSDDLQHAGNWLHVVKR 412
            .: |.:|....|| |:.|.:|.:                 ...::.|.|:..||..       |.
  Rat   351 QSYNGRLTGPAAVELKRLYQELQ-----------------IRNQLNQEQNSKLQQQ-------KE 391

  Fly   413 LFAADHLNRRLTQQALSEKNLTDRLIPSKGISKQMFEVLRSPDP----STSNSV 462
            |     ||:|..:.|:.:|.:::......|...|:..|..:..|    |||..|
  Rat   392 L-----LNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRV 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13875	NP_001261185.1	None
Ppp1r13b	XP_038968345.1	RA_ASPP1	101..183	CDD:340744	5/18 (28%)
		SMC_prok_B	<250..>426	CDD:274008	46/252 (18%)
		PHA03247	<576..992	CDD:223021
		Ank_2	1022..1108	CDD:403870
		ANK repeat	1022..1048	CDD:293786
		ANK repeat	1050..1081	CDD:293786
		ANK repeat	1083..1112	CDD:293786
		SH3	1152..1208	CDD:418401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000