Protein Alignment Vdup1 and Arrdc3

DIOPT Version :10

• Sequence 1: NP_612004.2
• Gene: Vdup1 / 38023
• FlyBaseID: FBgn0035103
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001036056.1
• Gene: Arrdc3 / 105171
• MGIID: 2145242
• Length: 414
• Species: Mus musculus
• Alignment Length: 321
• Identity: 88/321 - (27%)
• Similarity: 150/321 - (46%)
• Gaps: 26/321 - (8%)

  Fly     6 LKFLIIFDNTSLLYFPGQFLSGRVLIELQDETPALGLHFHVVGEGVVR--------NGRRQERTY 62
            :.|..:.|:...:|..|..:||||.:|:..|.....|..|..|...||        :.....:.|
Mouse    11 ISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNY 75

  Fly    63 DKE-NYIDFRMRLLG-----DVDQGGPAILSPGIHSFPFKLGLP-LGLPSTFLGRYGWIQFYCKA 120
            .:| .|.:.:..|:|     |..:.|...:..|.|.:.|...|| ..|.::|.||:|.::::.||
Mouse    76 TEEVEYFNHKDILIGHERDDDNSEEGFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKA 140

  Fly   121 ALRENNGIIHKNHQVFIVMNPIDLNLEKPILAQPFTCEVEHKLGVVCVGGGQIKCRVSLDRGGYV 185
            .|.....:..|..:.|.|...||:|  .|.|..|.....|..|.......|.|.....::|.||.
Mouse   141 ELHRPWLLPVKLKKEFTVFEHIDIN--TPSLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYT 203

  Fly   186 PGENILVTAFISNYSNVSIKRTKASLTETIEYLARGKVVQTEKRELAVLVRGK-IRPGAKDEWHN 249
            |||:|.:.|.|.|.|:..:. .||::.:|..:.|:||:  .|.::|...:||: :..|..:.|:.
Mouse   204 PGESIQIFAEIENCSSRMVV-PKAAIYQTQAFYAKGKM--KEVKQLVANLRGESLSSGKTETWNG 265

  Fly   250 ELY-VPPLPPTNLHGCHLIKISYDVFFVIE-PKSMEKEIKLQLPIVLATYPFRHSGDAVNA 308
            :|. :||:.|:.| .|.:|::.|.:...:: |.:|  ::.|.||:|:.|.|....|...::
Mouse   266 KLLKIPPVSPSIL-DCSIIRVEYSLMVYVDIPGAM--DLLLSLPLVIGTIPLHPFGSRTSS 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vdup1	NP_612004.2	Arrestin_N	8..145	CDD:451447	40/151 (26%)
		Arrestin_C	171..299	CDD:214976	40/130 (31%)
Arrdc3	NP_001036056.1	Arrestin_N	22..165	CDD:425619	38/142 (27%)
		Arrestin_C	187..314	CDD:214976	40/132 (30%)
		PPxY motif 1. /evidence=ECO:0000305	346..349
		PPxY motif 2. /evidence=ECO:0000305	391..394
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..414