Protein Alignment CG7049 and SUMF1

DIOPT Version :10

• Sequence 1: NP_612003.1
• Gene: CG7049 / 38022
• FlyBaseID: FBgn0035102
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: XP_011531926.1
• Gene: SUMF1 / 285362
• HGNCID: 20376
• Length: 448
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 160/364 - (43%)
• Similarity: 205/364 - (56%)
• Gaps: 58/364 - (15%)

  Fly    18 VSSDCGCQKLDRKAPDMPSISGQVCQQRAQGAHSHYRD------YYGELEPNIADMSLLPGGTVY 76
            ::..|||     ..|..|...|.     :..||.:.|:      ..||.:...:.|..:|.|...
Human    46 LAGSCGC-----GTPQRPGAHGS-----SAAAHRYSREANAPGPVPGERQLAHSKMVPIPAGVFT 100

  Fly    77 MGTDKPHFPADREAPERQVKLNDFYIDKYEVSNEAFAKFVLHTNYTTEAERYGDSFLFKSLLSPL 141
            ||||.|....|.|||.|:|.::.||:|.|||||..|.|||..|.|.||||::||||:|:.:||..
Human   101 MGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQ 165

  Fly   142 EQKNLEDFRVASAVWWYKVAGVNWRHPNGVDSDIDHLGRHPVVHVSWRDAVEYCKWAGKRLPSEA 206
            .:.|::. .||:|.||..|.|.|||||.|.||.|.|...|||:||||.|||.||.|||||||:||
Human   166 VKTNIQQ-AVAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEA 229

  Fly   207 EWEAACRGGKERKLFPWGNKLMPRNEHWLNIWQGDFPDGNLAEDGFEYTSPVDAFRQNIYDLHNM 271
            |||.:||||...:||||||||.|:.:|:.|||||:||..|..||||:.|:|||||..|.|.|:|:
Human   230 EWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNI 294

  Fly   272 VGNVWEWTADLWDVN---DVSDNP-------NRVKKGGSYLCHKSYCY----------------- 309
            |||.||||:|.|.|:   :.:.||       :||||||||:||:|..|
Human   295 VGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSQEYYDPYFQDVASEMLRRHT 359

  Fly   310 --RYR--------CAARSQN----TEDSSAGNLGFRCAK 334
              |::        |:.|...    .|..:.|....|||:
Human   360 ASRWKAFSSLEPCCSIRRHQQYAAIERLTCGKFELRCAE 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7049	NP_612003.1	FGE-sulfatase	65..334	CDD:397722	148/309 (48%)
SUMF1	XP_011531926.1	FGE-sulfatase	91..347	CDD:397722	141/256 (55%)