Protein Alignment CG7049 and SUMF2

DIOPT Version :10

• Sequence 1: NP_612003.1
• Gene: CG7049 / 38022
• FlyBaseID: FBgn0035102
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001353577.1
• Gene: SUMF2 / 25870
• HGNCID: 20415
• Length: 352
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 112/278 - (40%)
• Similarity: 147/278 - (52%)
• Gaps: 32/278 - (11%)

  Fly    67 MSLLPGGTVYMGTDKPHFPADREAPERQVKLNDFYIDKYEVSNEAFAKFVLHTNYTTEAERYGDS 131
            |..|.||...|||:.|. ..|.:.|.|:..:..|.||.:.|:|:.|..||....|.||||.:|.|
Human    30 MVQLQGGRFLMGTNSPD-SRDGDGPVREATVKPFAIDIFPVTNKDFRDFVREKKYRTEAEMFGWS 93

  Fly   132 FLFKSLLSPLEQKNLEDFRVASAVWWYKVAGVNWRHPNGVDSDIDHLGRHPVVHVSWRDAVEYCK 196
            |:|:..:|. |.:|.....:.|.:||..|....||.|.|..|.|.....|||:||||.||..||.
Human    94 FVFEDFVSD-ELRNKATQPMKSVLWWLPVEKAFWRQPAGPGSGIRERLEHPVLHVSWNDARAYCA 157

  Fly   197 WAGKRLPSEAEWEAACRGGKERKLFPWGNKLMPRNEHWLNIWQGDFPDGNLAEDGFEYTSPVDAF 261
            |.|||||:|.|||.|.|||.:.:::||||...|..   .|:|||.||.|:.|||||...|||:||
Human   158 WRGKRLPTEEEWEFAARGGLKGQVYPWGNWFQPNR---TNLWQGKFPKGDKAEDGFHGVSPVNAF 219

  Fly   262 -RQNIYDLHNMVGNVWEWTADLWDVNDVSDNPNRVKKGGSY-------------------LCHKS 306
             .||.|.|::::||||||||..:   ..::...||.:|.|:                   ||
Human   220 PAQNNYGLYDLLGNVWEWTASPY---QAAEQDMRVLRGASWIDTADGSANHRARVTTRVLLC--- 278

  Fly   307 YCYRYRCAARSQNTEDSS 324
             |..:...|:||.|..|:
Human   279 -CPGWSAVAQSQLTTASN 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7049	NP_612003.1	FGE-sulfatase	65..334	CDD:397722	112/278 (40%)
SUMF2	NP_001353577.1	FGE-sulfatase	26..274	CDD:397722	104/251 (41%)