DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dic61B and CG13074

DIOPT Version :9

Sequence 1:	NP_728477.1	Gene:	Dic61B / 38020	FlyBaseID:	FBgn0263988	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_648835.1	Gene:	CG13074 / 39760	FlyBaseID:	FBgn0036567	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	161	Identity:	30/161 - (18%)
Similarity:	58/161 - (36%)	Gaps:	61/161 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   440 SPFLPSLLA---------IGLY------DGSVEVRDVSSLQDTPVAVSQRSTSPGSSPVVAIRWI 489
            :||..::.|         |.||      |.||:::.:.|:..|..|            .||:.|.
  Fly   195 NPFNKTMFAGSTMDGELFIWLYEQARGSDSSVDIKQLYSVSSTQGA------------AVALDWP 247

  Fly   490 KQVSDDDHETDIDPFLSLSQDGSVTRFRIIKSPFLLGFTQMILERVEGHPEGIFVHPSSRIPCES 554
            ::          ...|:...:|||.::.:.:        ||.|:.....|..:...|::.:
  Fly   248 RE----------HLLLACFANGSVRQWDLSR--------QMALDWEYTLPATVSSEPTAMV---- 290

  Fly   555 NRHPQGLSITTHPLHKDIYYVLTDEGCIHKC 585
                        .|..|.:.|.|::|.:::|
  Fly   291 ------------TLGLDDFVVGTNDGGVYRC 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dic61B	NP_728477.1	WD40	358..730	CDD:225201	30/161 (19%)
		WD40 repeat	381..429	CDD:293791
		WD40	433..711	CDD:295369	30/161 (19%)
		WD40 repeat	434..473	CDD:293791	12/47 (26%)
		WD40 repeat	552..599	CDD:293791	6/34 (18%)
		WD40 repeat	604..637	CDD:293791
		WD40 repeat	645..682	CDD:293791
		WD40 repeat	691..727	CDD:293791
CG13074	NP_648835.1	WD40 repeat	189..234	CDD:293791	9/38 (24%)
CG13074	NP_648835.1	WD40 repeat	242..275	CDD:293791	10/50 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100