Protein Alignment Dic61B and Dnai2

DIOPT Version :9

• Sequence 1: NP_728477.1
• Gene: Dic61B / 38020
• FlyBaseID: FBgn0263988
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 113/565 - (20%)
• Similarity: 205/565 - (36%)
• Gaps: 133/565 - (23%)

  Fly   244 ILITKATVSSYVSNFEMYDTLNNITKEFATATMSSVKDLTSALAQT-----------EDADTFED 297
            ::.|:.:....|.::.:.:.::.:| ::|..|..||.:...|..::           :|.:..:.
  Fly    24 VVFTENSNPELVKSYILKNPVDRVT-QYAGQTSLSVANTERATYKSTGITHNEGGWPKDINMHDP 87

  Fly   298 DEAVAEKDKVS------SQIERLFRSPEFRNAIMYMGRTLSSNTNEAGLRRFRNFDQVERWNAEA 356
            ::.|..|.|:.      :|:..|.:..|.     |:.:..:.|..|   ..|.|.|...
  Fly    88 EQTVRYKRKIEKDENYITQVMNLTKPMEH-----YIHQNNAVNIYE---NYFENLDPAP------ 138

  Fly   357 EYVYSMNLLFRLVPEPSKDE-----------RKAVSDIDFCRSNGDILAVAYGLYSFSSQHVPTS 410
                        :|||.|..           :..|..:.:....|..:||::....|........
  Fly   139 ------------LPEPCKSRTVNVYRDPNPIKVPVKHLSWSPDGGIKMAVSHCDMRFQGDKSNQK 191

  Fly   411 GSVFLWSIKNPGEPERAYYYDVPVTAINFSPFLPSLLAIGLYDGSVEVRDVSSLQDTPVAVSQRS 475
            .:.::|.::||.||.......||...:.::...|:.|..|:|:|.|...|... ...||.:|:|.
  Fly   192 CNSYIWEVENPNEPFLTLEPKVPCVCLEYNQKDPTSLVSGMYNGQVAAWDTRH-GKLPVMISERE 255

  Fly   476 TSPGSSPVVAIRWIKQVSDDDHETDIDPFLSLSQDGSVTRF--RIIKSPFLLGFTQMILERVEGH 538
            .. ...||.::.|....|..:       |.|...||.|..:  |.:..|    ..:::::.|:..
  Fly   256 VC-HRDPVNSVLWNNSKSGTE-------FFSGGSDGQVLWWDTRKLTEP----LDRLLMDPVKSD 308

  Fly   539 PEGIFVHPSSRIPCESNRHPQGLSI----TTHPLHKDIYYVLTDEGCIHKCSINYQHQYLEV--- 596
            .:.:     ||        ..|:|:    ||.|..   :...|:.|.:..|:...:....::
  Fly   309 DQDL-----SR--------SYGISVLEYETTIPTR---FMAGTEMGMLFSCNRKGKTPTEKIQIR 357

  Fly   597 LRCHDGGVTVMEFSPWSPKLFLTCGNDWFVRIWVDGITRPLLELLDEMTPVHWAK---------- 651
            :.||.|.|..:..:|...|.|||.| ||..|||.:....         :.:.|.|
  Fly   358 MMCHLGPVYAITRNPAFVKNFLTVG-DWCARIWSEDCRE---------SSIIWTKSSSSMLTDGA 412

  Fly   652 WSPTH-STIIVTVNRETANVWDFRRNLLRPMSKHKMDSSFNTVARFSHCGRTLVIGNERG----- 710
            ||.|. |...:|......:.||..:....|:...|:........|.:..|:.:..|::.|
  Fly   413 WSYTKVSQFFITRMDGVLDTWDLLQQQNEPVLTVKVCDEPLYCVRTNENGKFVSCGSQLGATFLV 477

  Fly   711 ----NTLFNALNDMPFSPHFQYDELEKAIFKAIGNDHELLMELKS 751
                |.:.:|.||.|         |..|:|:. .|..|.::|.||
  Fly   478 EVSDNMVMSAKNDKP---------LLTAMFER-ENRREKILEAKS 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic61B	NP_728477.1	WD40	358..730	CDD:225201	84/411 (20%)
		WD40 repeat	381..429	CDD:293791	9/47 (19%)
		WD40	433..711	CDD:295369	64/306 (21%)
		WD40 repeat	434..473	CDD:293791	9/38 (24%)
		WD40 repeat	552..599	CDD:293791	8/53 (15%)
		WD40 repeat	604..637	CDD:293791	12/32 (38%)
		WD40 repeat	645..682	CDD:293791	10/47 (21%)
		WD40 repeat	691..727	CDD:293791	9/44 (20%)
Dnai2	NP_001261723.1	WD40	<160..482	CDD:225201	75/360 (21%)
		WD40 repeat	162..208	CDD:293791	9/45 (20%)
		WD40	212..469	CDD:295369	63/295 (21%)
		WD40 repeat	215..254	CDD:293791	10/39 (26%)
		WD40 repeat	262..304	CDD:293791	10/52 (19%)
		WD40 repeat	318..355	CDD:293791	7/39 (18%)
		WD40 repeat	365..401	CDD:293791	12/45 (27%)
		WD40 repeat	408..433	CDD:293791	5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435274
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1587
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840