Protein Alignment Dic61B and CG14838

DIOPT Version :9

• Sequence 1: NP_728477.1
• Gene: Dic61B / 38020
• FlyBaseID: FBgn0263988
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: NP_648138.1
• Gene: CG14838 / 38851
• FlyBaseID: FBgn0035799
• Length: 1132
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 102/613 - (16%)
• Similarity: 184/613 - (30%)
• Gaps: 211/613 - (34%)

  Fly   266 NITKEFATATMSSVKDLTSALAQT-----------------------EDADTFEDDEAVAEKDKV 307
            |:||:....::.|.........||                       ::.|..|::|....:.|.
  Fly   262 NVTKKRVNVSVQSAPPKIEREQQTNPTFPSNAWSQYLYEIDDEDLELDETDVDEEEEKKKAQAKP 326

  Fly   308 SSQIERLFRSPEFRNAIMYMGRTLSSNTNEAGLRRFRNFDQVERWNAEAEYVYSMNLL------- 365
            .:.:|...:.||....|..:..||             .|:|::.:..:...:.|..::
  Fly   327 GTYVEPEKKPPEMSAQIEMLLNTL-------------EFNQIDSYRDDYSLISSRQVVQYTNPYL 378

  Fly   366 --FRLVPEPSKDERKAVSDIDFCRSNGDILAVAYGLYSFSSQHVPTS------------GSVFLW 416
              |......||..::.|:..|:......::||:|...:.::.:..|:            ..|.||
  Fly   379 QEFLCFANISKSNKRFVAGYDWYPKLSGLIAVSYAFSTPATVNEATNRVDYVQRAVLEPNPVLLW 443

  Fly   417 SIKNPGEPERAYYYDVPVTAINFSPFLPSLLAIGLYDGSVEVRDVS------------------- 462
            |..:....:..:...:..||:.|.||...:|..|..:|.|.:.|:.
  Fly   444 SFSDNLNYKLEFEAPIETTALTFCPFNGDILLGGSKNGQVVLWDLQGRCEKLDEEEYLTAAQAKY 508

  Fly   463 ------------SLQD---TPVAVSQRSTSPGSSPVVAIRWI----------KQVSDDDHETDID 502
                        .::|   .|..:|....|| ...:.|..|:          |..:|.|......
  Fly   509 RIMIGEFLNWTIDIEDNVIVPATISLLDCSP-KGAITAFYWLGRSIYLSQFGKVYNDPDIRNHHK 572

  Fly   503 PFLSLSQDGSVT--------------------------------RFRIIKSPFLLGFTQMILERV 535
            .|::.:.||:::                                :..:||..:.|.|.:.|
  Fly   573 FFVTCAFDGTISFWDLDGKGGKSAKDKMRNRMLPKELTQSESAFKSMVIKPTYNLYFPEPI---- 633

  Fly   536 EGHPEGIFVHPSSRIPCESNRHPQGLSITTHPLHKDIYYVLTDEGCI-----------HKCSINY 589
                .||....|    |.|...|....|..:|.:..|..:..|...:           |...|::
  Fly   634 ----TGIIADTS----CLSCLTPVAKLIQANPSNYPIKTIAKDPPTMRQSMIVSTFYGHVSRIDW 690

  Fly   590 QHQYLE------------VLRCHDGGVTVMEFSPWSPKLFLTCGNDWFVRIWVDGITRPLLELLD 642
            |..|.|            ....|||.|.:::.:|:.|:||.:.|.. .:.||.:..
  Fly   691 QGTYTEGEATEVINSSIPFAMVHDGPVVMVKKNPFYPELFASIGRT-ILAIWKEDY--------- 745

  Fly   643 EMTPVHWAK---------WSPTHSTIIVTVNRE-TANVWDFRRNLLRPMSKHKMDSSFNTVARFS 697
            ..:|:.|.|         ||.|...::.....: ....||.                   :||..
  Fly   746 NYSPIFWRKRACDLTAVAWSETRPAVLYLTRIDGILEAWDI-------------------LARDD 791

  Fly   698 HCGRTLVIGNERGNTLFNALNDMPFSPH 725
            ....|.::|   |..:.......|..||
  Fly   792 DACLTEILG---GGIITAITEHRPSLPH 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic61B	NP_728477.1	WD40	358..730	CDD:225201	84/498 (17%)
		WD40 repeat	381..429	CDD:293791	9/59 (15%)
		WD40	433..711	CDD:295369	66/386 (17%)
		WD40 repeat	434..473	CDD:293791	12/72 (17%)
		WD40 repeat	552..599	CDD:293791	12/69 (17%)
		WD40 repeat	604..637	CDD:293791	8/32 (25%)
		WD40 repeat	645..682	CDD:293791	8/46 (17%)
		WD40 repeat	691..727	CDD:293791	8/35 (23%)
CG14838	NP_648138.1	WD40	328..>599	CDD:225201	45/284 (16%)
		WD40 repeat	462..505	CDD:293791	10/42 (24%)
		WD40 repeat	510..547	CDD:293791	6/37 (16%)
		RE_R_Pab1	807..>863	CDD:286594	3/10 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1587
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840