Protein Alignment Dic61B and LOC1279985

DIOPT Version :10

• Sequence 1: NP_728477.1
• Gene: Dic61B / 38020
• FlyBaseID: FBgn0263988
• Length: 764
• Species: Drosophila melanogaster
• Sequence 2: XP_319777.5
• Gene: LOC1279985 / 1279985
• VectorBaseID: AGAMI1_006308
• Length: 745
• Species: Anopheles gambiae
• Alignment Length: 545
• Identity: 104/545 - (19%)
• Similarity: 178/545 - (32%)
• Gaps: 194/545 - (35%)

  Fly   327 MGRTLSSNTNEAGLRRFRNFDQVERWNAEAEYVYSMNLLFRLVPEPSKDERKAVSDIDFCRSNGD 391
            |.|.|      .|.|..|..|    |:.|....:..:..|.   .|:|...|..:     :|...
Mosquito     1 MNRAL------CGGRTVRTLD----WHPELSGCFVASYTFE---TPAKHANKQHN-----QSEQP 47

  Fly   392 ILAVAYGLYSFSSQHVPTSGSVFLWSIKNPGEPERAYYYDVPVTAINFSPFLPSLLAIGLYDGSV 456
            ..|.|.|..:|.      ..:|.|||.::..||.........|||:.|.|:...||..||.:|.:
Mosquito    48 AGADALGRMTFE------KCTVLLWSFEDSLEPALELKTIREVTAVAFCPYDGELLVGGLANGQI 106

  Fly   457 EVRDVSS------------------------LQDTPVAVSQ--RSTSPGS---------SPVVAI 486
            .:.|:..                        |.|.| ||.:  |..:|.:         :.:..:
Mosquito   107 VLWDLGGELERVEQANRDARGASEYRKQARHLMDYP-AVERIDREVNPAAVSSLEHSSRAAITCV 170

  Fly   487 RWIKQ----VSDDDHETDIDP----FLSLSQDGSVTRFRIIKSPFLLGFTQMILERVEG------ 537
            :|:.:    .|....::..|.    .::.:.||||..:.       |.||...|:::..
Mosquito   171 KWLPRNYYCTSTGHLKSHADKLYRFMMTTALDGSVCFWD-------LEFTMPALQKLIAASKTAQ 228

  Fly   538 --------HPEGIFVHPSSRIPCESNRHPQGLSITTHPLHKDIYYVLTDE--------------- 579
                    ....:| .|:.::.||       |.|.:..:.:.:|..:..|
Mosquito   229 QADRTMYQRVNNLF-FPTFKLVCE-------LPILSVVIDEAVYLSMPLETVTELTVRVKHQQQP 285

  Fly   580 ---GC----------------------------IHKCSINYQHQYLEVLRCHDGGVTVMEFSPWS 613
               ||                            ::...:..||.:.::   |:|.|..:|.:|..
Mosquito   286 VPVGCEMLLKVGSYTGQLIEGSWEGYDFEQGALVNDEPVKVQHVFGQI---HNGPVLALERNPHC 347

  Fly   614 PKLFLTCGNDWFVRIWVDGITRPLLELLDEMTPVHWAK---------WSPTH-STIIVTVNRETA 668
            ..:||:.|.: .:.||.:.         |:.:||.|.|         ||... |...:.::....
Mosquito   348 RSVFLSIGGN-VLAIWAED---------DKSSPVFWRKKAEMITACRWSLDRVSVFFIGLSNGDF 402

  Fly   669 NVWD-----FRRNL--------LRPMSKHKMDSSFNTVARFSHCGRTLVIGNERGNTLFNALNDM 720
            .:||     ||..:        |..:|:|::.|:.|.:|...|.....:.  :...|..|.|.|
Mosquito   403 EIWDMSLKTFRATVCLNLGSEALTTISQHRLASARNCLAVADHNANIRIF--KLAPTFVNPLPD- 464

  Fly   721 PFSPHFQYDELEKAIFKAIGNDHEL 745
                       |...|:.:.| |||
Mosquito   465 -----------EVETFQRMMN-HEL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic61B	NP_728477.1	WD40 repeat	381..429	CDD:293791	11/47 (23%)
		WD40	433..711	CDD:475233	70/403 (17%)
		WD40 repeat	434..473	CDD:293791	16/62 (26%)
		WD40 repeat	552..599	CDD:293791	10/92 (11%)
		WD40	<594..>710	CDD:441893	29/138 (21%)
		WD40 repeat	604..637	CDD:293791	8/32 (25%)
		WD40 repeat	645..682	CDD:293791	12/59 (20%)
		WD40 repeat	691..727	CDD:293791	7/35 (20%)
LOC1279985	XP_319777.5	None