Protein Alignment CG6845 and DCSTAMP

DIOPT Version :10

• Sequence 1: NP_612000.3
• Gene: CG6845 / 38019
• FlyBaseID: FBgn0035099
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_110415.1
• Gene: DCSTAMP / 81501
• HGNCID: 18549
• Length: 470
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 113/541 - (20%)
• Similarity: 200/541 - (36%)
• Gaps: 161/541 - (29%)

  Fly    67 VRCIVTLALPSLCSSRGRAFLISL-----AFVIAAVGPTANILANLKVMLRSLACGQELLRQALG 126
            |.|:|.|....|.|.....||.|:     :::|..|....:..|...::|..|:||
Human    35 VCCLVALISVGLLSVAACWFLPSIIAAAASWIITCVLLCCSKHARCFILLVFLSCG--------- 90

  Fly   127 QMLDVILEPVNAIQLAVDLLMREVRRVLKLAMVVLLRIQDQLIAIIKTLKNCAAWLKSIVD--LC 189
                                :||.|..|..|        ...|.|:..::|.....|.::|  .|
Human    91 --------------------LREGRNALIAA--------GTGIVILGHVENIFHNFKGLLDGMTC 127

  Fly   190 NTEMGTPWARCKKTAHHAMIRCQSKMGVFKALCHAAKLFLALCYPAKIIDVFCSGYWDL-SWGLL 253
            |       .|.|..:.|        ..:.|....|.:....|..|..:.|       || ||...
Human   128 N-------LRAKSFSIH--------FPLLKKYIEAIQWIYGLATPLSVFD-------DLVSWNQT 170

  Fly   254 DKIAERYREFVRHIEEMFDANITFEHEFFFDTNSSKSLTDVGE------------EILQDINKRL 306
            ..::            :|..:...|.:.    |.||     ||            |:|..:.::|
Human   171 LAVS------------LFSPSHVLEAQL----NDSK-----GEVLSVLYQMATTTEVLSSLGQKL 214

  Fly   307 SSFIFLSSFVDILCWVMVVTVFFKATIFYLRYMH--SRQFQNVFLTKILSDIDRRHEKHGYDP-L 368
            .:|..||            .|.....:|..|::.  ..:::|:::|:.....|.| |:|...| :
Human   215 LAFAGLS------------LVLLGTGLFMKRFLGPCGWKYENIYITRQFVQFDER-ERHQQRPCV 266

  Fly   369 LPLHQLERAKYMKLTSL--------RLTLFEFVSIVENACFMATTCLQLFAICFLDYGLFWLLAT 425
            |||::.||.||:.:.:.        .|.|| |:.|:.:.|...     |||.  :||.|:.|:.:
Human   267 LPLNKEERRKYVIIPTFWPTPKERKNLGLF-FLPILIHLCIWV-----LFAA--VDYLLYRLIFS 323

  Fly   426 ISLHGHQETGLEVPAYVDLEIKGGGFVADVMRGIANAFRPLTQKSILDVNPCLPLP---VKPDYA 487
            :|.......|.||...:..|.:|   ..|::..  ::|    ..|:.:.| |:|.|   :...:.
Human   324 VSKQFQSLPGFEVHLKLHGEKQG---TQDIIHD--SSF----NISVFEPN-CIPKPKFLLSETWV 378

  Fly   488 EYLIILLLCLLAWLILLAEPYILRTRHLIMAHFYPKRAKERGMFLYNMISEDRTSIFKFIRRRKR 552
            ...:|||:.::..|:   ...:::.:.|:.|.|||...::|..:|:          .|.:::|.:
Human   379 PLSVILLILVMLGLL---SSILMQLKILVSASFYPSVERKRIQYLH----------AKLLKKRSK 430

  Fly   553 ---NEFNHTRNVKHTRNYTWL 570
               .|.....::..|:.:.||
Human   431 QPLGEVKRRLSLYLTKIHFWL 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6845	NP_612000.3	DC_STAMP	344..533	CDD:462265	50/200 (25%)
DCSTAMP	NP_110415.1	DC_STAMP	242..421	CDD:462265	50/200 (25%)