Protein Alignment CG6845 and Dcst1

DIOPT Version :10

• Sequence 1: NP_612000.3
• Gene: CG6845 / 38019
• FlyBaseID: FBgn0035099
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_084250.1
• Gene: Dcst1 / 77772
• MGIID: 1925022
• Length: 732
• Species: Mus musculus
• Alignment Length: 689
• Identity: 148/689 - (21%)
• Similarity: 256/689 - (37%)
• Gaps: 131/689 - (19%)

  Fly    41 GHLVLGLNLTFAIPVAL-----VLAVF-----------YSRPVRCIVTLALPSLCSSRGRAFLIS 89
            |.|.:||......|:.:     |:|::           .|..:||...|.:|.:....||.|::.
Mouse    86 GLLAIGLFQLLVNPMNIYEEQKVVALYCLASLGAIGWGTSPHIRCASLLLVPKMLGKEGRLFVMG 150

  Fly    90 LAFVIAAVGPTANILANLKVMLRSLACGQELLRQALGQMLDVILEPVNAIQLAV----DLLMREV 150
            .|......||.||:.:|:..::.||.|..||..........|...|:.|:...:    |.|.:|:
Mouse   151 YALAAIYSGPAANLRSNINEVIASLGCTVELQINNTRSAWRVSTAPLRAVFKGMVGSKDSLNKEI 215

  Fly   151 RRV----------------------------------------LKLAMVVLLRIQDQLIAII-KT 174
            :.|                                        |...||..||.:.:.|.:: |.
Mouse   216 QNVSTSFEEMDEQVKSDAGYSSEDWDKNRESTEMFGTSRVRPYLSTQMVYELRTRLRCIHVVNKA 280

  Fly   175 LKNCAAWLKSIVDLCNTEMGTPWARCKKTAHHAMIRCQSKMGVFKALCHAAKLFLALCYPAKIID 239
            :.:|..|.......|...:..|       ..:.||....|   ||.||:.||:....||....::
Mouse   281 ILSCYRWFDKKHKNCMRRIHLP-------LFNNMICVPMK---FKFLCNIAKVIEIWCYKRIPVE 335

  Fly   240 VFCSGYWDLSWGLLDKIAERYREFVRHIEEMFDANITFEHEFFFDTNSSKSLT-----DVGEEIL 299
                       |...:..:...:.:..:...|.|||..:.|   ..:|...|.     .:|.|:.
Mouse   336 -----------GNFGQTYDSVNQSIHGLSGEFSANINLKEE---KQSSMVGLNTTNWEHMGTEVR 386

  Fly   300 QDINKRLSSFIFLSSFVDILCWVMVVTVFFKATIFYLRYMHSRQFQNVFLTKILSDIDRRHEKHG 364
            ..:.::.:...:....:.:|.....:.||..|..:...|....:|.|::::.....||.|.:|.|
Mouse   387 DYVRQQETYLQWAMGLLHVLLSCTFLLVFHSAFSYMDHYNWDIRFDNIYISTYFCQIDARRKKLG 451

  Fly   365 YDPLLPLHQLERAKYMKLTSLRLTLFEFVSIVENACFMATTCLQLFAICFLDYGLFWLLATISLH 429
            ...||||.:.||...:......:..:|...::..........|.|..:|.:|:.|:.:..||..|
Mouse   452 KQSLLPLRKAERKTVIFPFKATIQAWEMRYVIRELLETLPIVLLLLVLCAIDWALYSVFDTIRQH 516

  Fly   430 GHQETGLEVPAYVDLEIKGGGFVADVMRGIANAFRPLTQKSILDVN----PCLPLPVKPDYAEYL 490
            ...:........::::::|...:|.::|....|   |...|..||.    ||||.|:..:..:|.
Mouse   517 SFVQYSFRSSHKLEIKVEGDSILAKLLRKTIGA---LNTSSSTDVETNNMPCLPQPISLNARDYF 578

  Fly   491 IILLLCLLAWLILLAEPYILRTRHLIMAHFYPKRAKERGMFLYNMISEDRTSIFK-----FIRRR 550
            ...|..||...:.||:.:..|.|.:|.|.::|||.|:|.:|.||...:.|::..|     .:||.
Mouse   579 KASLPTLLLVCLCLAQAFGYRLRRVIAAFYFPKREKKRALFFYNEFLKKRSAFTKLRRAAIVRRA 643

  Fly   551 KRNEFNHTRNVKHTRNYTWLNNRFSCLMCMCSCCSSCQSTERCTICGRSLTLSNRNPCDTPGCKG 615
            .:.:......|:.......|.:||              ..:||.:| :::...:...|.||.||.
Mouse   644 NQQKAPPHYLVEALYRRCPLLHRF--------------MRQRCVVC-QAMETPDSYVCPTPDCKA 693

  Fly   616 VYCGKCFEKSHNKCCLC--------------NRPVDYGD 640
            :||..|::.....|.:|              |....|||
Mouse   694 LYCRSCWDDMQRLCPVCTPREELSSSAHSDSNDDAVYGD 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6845	NP_612000.3	DC_STAMP	344..533	CDD:462265	51/192 (27%)
Dcst1	NP_084250.1	DC_STAMP	431..621	CDD:462265	51/192 (27%)