Protein Alignment CG6845 and Dcst2

DIOPT Version :10

• Sequence 1: NP_612000.3
• Gene: CG6845 / 38019
• FlyBaseID: FBgn0035099
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: XP_011238650.1
• Gene: Dcst2 / 329702
• MGIID: 2685606
• Length: 758
• Species: Mus musculus
• Alignment Length: 654
• Identity: 185/654 - (28%)
• Similarity: 310/654 - (47%)
• Gaps: 39/654 - (5%)

  Fly    24 GYLCGLAVTLAWNWWQL---GHLVLG-LNLTFAIPVALVLAVFYSRPVRCIVTLALPSLCSSRGR 84
            |:..||::..|:...:|   ||...| |..|..:...|.|.:.:||.||..|.|.||...|.:.|
Mouse    17 GFTVGLSLATAFGLLELLGEGHSPFGCLVTTVTLAAFLSLGMGFSRQVRVSVLLLLPQAFSKQSR 81

  Fly    85 AFLISLAFVIAAVGPTANILANLKVMLRSLACGQELLRQALGQMLDVILEP-VNAIQLAVDLLMR 148
            ..|:..:|.:...||.||.|.|......::|||.||......:||:...:| ::|:.
Mouse    82 LLLLVASFGLVLQGPCANTLQNFTRASEAVACGAELALNQTAEMLERAKQPLISALS-------- 138

  Fly   149 EVRRVLKLAMVVLLRIQ-------DQLIAIIKTLKNCAAWLKSIVDLCNTEMGTPWARCKKTAHH 206
            :::.:.:.|.||..||:       |.:..|.:.|:|...||..|.|:||:|:|.|:::|.:....
Mouse   139 KIKAIAQKAKVVGDRIRKFFRSIIDAVKHIARCLQNVWYWLLHIGDMCNSELGNPYSKCTQVFDD 203

  Fly   207 AMIRCQSKMGVFKALCHAAKLF-LALCYPAKIIDVFCSGYWDLSWGLLDKIAERYREFVRHIEEM 270
            |.|.|...:..|..||:|...: |.:|..|.::..||.....|.:.|...|.....:.:..:...
Mouse   204 AKIHCMKVVSGFPHLCYALLPYKLLVCGLASLVQKFCVLPSYLEFFLRTVIRTPVMKLLGKLRRE 268

  Fly   271 FDANITFEHEFFFDTNSSKSLTDVGEEILQDINKRLSSFIFLSSFVDILCWVMVVTVFFKATIFY 335
            |:.|:|..|.|..|.|||:||:.|..::.:.::.:|.:.....|.:.....:::..::.:|..:.
Mouse   269 FEFNMTATHYFSVDLNSSRSLSQVALDLQEAVSMKLYTAREALSLMGYTMPLLIGFLYIQALCYR 333

  Fly   336 LRYMHSRQFQNVFLTKILSDIDRRHEKHGYDPLLPLHQLERAKYMKLTSLRLTLFEFVSIVENAC 400
            ..|::|.:|.||::|:...|::......|...:|||...|...|::..|:.|:..|.:.......
Mouse   334 YYYLNSDKFDNVYITRRFLDMEAVRSLAGMPTVLPLSSHEAKHYIQPDSMFLSQREQMFYTLEIF 398

  Fly   401 FMATTCLQLFAICFLDYGLFWLLATISLHGHQETGLEVPAYVDLEIKGGGFVADVMRGIANAFRP 465
            .:....|.:..:.|||||:||||.....|...|.....|..|.:.::|.|:..::.|.:|:||..
Mouse   399 NLTRHLLIMLLLVFLDYGVFWLLDLARYHLQGEIVARSPVVVSISVEGSGYSGNIYRDLASAFDV 463

  Fly   466 LTQKSILDVNP-CLPLPVKPDYAEYLIILLLCLLAWLILLAEPYILRTRHLIMAHFYPKRAKERG 529
            :.|.::..::| |...|.:||...|::|..:..|.:.:.|...|:.|.|..|.|.:||.|.:||.
Mouse   464 MQQGNVSVLSPRCTLHPSEPDAKGYIVIGTMYGLCFFVTLFGSYVSRLRRAICASYYPSREQERI 528

  Fly   530 MFLYNMISEDRTSIFKFIRR--RKRNEFNHTRNVKHTRNYTWLNNRFSCLMCMCSCCSSCQSTER 592
            .:||||:...||:|...::|  |:|:......|:...     |..|...|..:....|..||  .
Mouse   529 TYLYNMLLSHRTNITATVQRAVRRRSADQGQMNILQV-----LAIRLPFLRPLLGPFSLQQS--Y 586

  Fly   593 CTICGRSLT---LSNRNPCDTPGCKGVYCGKCFEKSHNKCCLCNRPVDYGDFSDVTEVDDSSDYS 654
            |..||....   :.|...|.||||:|:||..||...:|.|.:|:.|:     |:...:|...|.|
Mouse   587 CMGCGEPEDKGGMENFVSCSTPGCRGLYCPTCFRLLNNTCSVCSAPL-----SNQGHLDLELDSS 646

  Fly   655 EKES 658
            ::||
Mouse   647 DEES 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6845	NP_612000.3	DC_STAMP	344..533	CDD:462265	54/189 (29%)
Dcst2	XP_011238650.1	DC_STAMP	342..532	CDD:462265	54/189 (29%)