Protein Alignment CG6845 and Dcst1

DIOPT Version :10

• Sequence 1: NP_612000.3
• Gene: CG6845 / 38019
• FlyBaseID: FBgn0035099
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_001419993.1
• Gene: Dcst1 / 295246
• RGDID: 1307756
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 736
• Identity: 162/736 - (22%)
• Similarity: 270/736 - (36%)
• Gaps: 151/736 - (20%)

  Fly    21 VIGGYL-CGLAVTLAWN---WWQLGH---------------LVLGLNLTFAIPVAL-----VLAV 61
            :|.|.| .||.|  :|:   |.|.|.               |.:||......|:.:     |:|:
  Rat    49 IIQGLLRWGLPV--SWSRFLWRQPGEFPVTAFLLGTGTGGLLAIGLFQLLVNPMNIYEEQKVVAL 111

  Fly    62 F-----------YSRPVRCIVTLALPSLCSSRGRAFLISLAFVIAAVGPTANILANLKVMLRSLA 115
            :           .|..:||...|.:|.:....||.|::..|......||.||:..|:..::.||.
  Rat   112 YGLTSLGAIGWGISPHIRCASLLLVPKMLGKEGRLFIMGYALASIYKGPVANLQYNINEVIASLG 176

  Fly   116 CGQELLRQALGQMLDVILEPVNAI----QLAVDLLMREVRRVLKL-----AMV------------ 159
            |..||..........|...|:.|:    ..:.|.|..|:..|...     |.|
  Rat   177 CTVELQINNTRSAWRVSTAPLRAVFKDMLSSKDSLKTEIANVSTSFEDLDAQVESNIGYSPEDKD 241

  Fly   160 ----------------VLLRIQDQLIAIIKTLKNCAAWLKSIVDLCNTEMGTPWARCKKTAHHAM 208
                            ..|.:..|::..:||...|:..:...:..|.........||       |
  Rat   242 MDTAPGTKALGTGTSRARLHLSTQMVYELKTKLRCSHVVNKAILSCYRWFDKKHQRC-------M 299

  Fly   209 IRCQSKMGVFKALCHAAKLFLALCYPAKIIDVFCSGYWDLSWGLLDKIAERYREFVRHIEEMFDA 273
            .|.|..: :...||...| |...|..||:::::|.....:. |...:..:...:.:..:...|.|
  Rat   300 QRIQVPL-LNSLLCLPMK-FKFFCNIAKVMEIWCHKRIPVE-GNFGQTYDSVNQSIHGLSGEFSA 361

  Fly   274 NITFEHEFFFDTNSSKSLTDVG---------EEILQDINKRLSSFIFLSSFVDILCWVMVVTVFF 329
            ||        |....|....||         .|:....:::.:...:....:.:|.....:.||.
  Rat   362 NI--------DIKEQKQSAVVGLSTNWEHVSVEVRDYAHQQEARLQWAVGLMHVLLSCTFLLVFH 418

  Fly   330 KATIFYLRYMHSRQFQNVFLTKILSDIDRRHEKHGYDPLLPLHQLERAKY-------MKLTSLRL 387
            .|..:...|....:|.|::::.....||.|.:|.|...||||.:.|:...       ::.|.:|.
  Rat   419 AAFSYMDNYNWDIRFDNIYISTYFYQIDARRKKLGKQSLLPLRKAEKTSVIFPLKATIQATEMRN 483

  Fly   388 TLFEFVSIVENACFMATTCLQLFAICFLDYGLFWLLATISLHGHQETGLEVPAYVDLEIKGGGFV 452
            .:.|.:..:.    :....|.||||   |:.|:.:..||..|...:........:::.::|...:
  Rat   484 VIRELLETLP----ILLLLLVLFAI---DWVLYSIFDTIGHHSFVQYSFRSSHKLEINVEGDSIL 541

  Fly   453 ADVMRGIANAFRPLTQKSILDVN--PCLPLPVKPDYAEYLIILLLCLLAWLILLAEPYILRTRHL 515
            |.::|....|.. .|..:.::.|  ||||..|......|....|...|...:.||:.:..|.|.:
  Rat   542 ARLLRKTIGALN-TTSDTEMETNNMPCLPRAVGLSAGGYFRASLPTCLLMCVCLAQAFGYRLRRV 605

  Fly   516 IMAHFYPKRAKERGMFLYNMISEDRTSIFKFIRRRKRNEFNHTRN---VKHTRNYTW-------- 569
            |.|.::|||.|:|.:||||.:            .|||:.|...|.   |:..|..|.
  Rat   606 IAAFYFPKREKKRVLFLYNEL------------LRKRSAFTKLRRAAIVRRARQQTTPRPPVVDA 658

  Fly   570 LNNRFSCLMCMCSCCSSCQSTERCTICGRSLTLSNRNPCDTPGCKGVYCGKCFEKSHNKCCLCNR 634
            |..|...|..:        :..||.:| ::|.......|.||.||.:||..|::....:|.:|.
  Rat   659 LYRRCPLLRRL--------TRRRCVVC-QALETPESYVCPTPDCKALYCRSCWDDMQRQCPVCT- 713

  Fly   635 PVDYGDFSDVTEVDDSSDYSE 655
            |.:....|..::.:|.:.|.|
  Rat   714 PREELSSSAHSDSNDDTVYGE 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6845	NP_612000.3	DC_STAMP	344..533	CDD:462265	51/197 (26%)
Dcst1	NP_001419993.1	DC_STAMP	433..623	CDD:462265	51/197 (26%)