Protein Alignment CG6845 and DCST2

DIOPT Version :10

• Sequence 1: NP_612000.3
• Gene: CG6845 / 38019
• FlyBaseID: FBgn0035099
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_653223.2
• Gene: DCST2 / 127579
• HGNCID: 26562
• Length: 773
• Species: Homo sapiens
• Alignment Length: 654
• Identity: 185/654 - (28%)
• Similarity: 303/654 - (46%)
• Gaps: 43/654 - (6%)

  Fly    22 IGGYLCGLAVTLAWNWWQL---GHLVLG-LNLTFAIPVALVLAVFYSRPVRCIVTLALPSLCSSR 82
            :||:..||::..|:...:|   ||...| |..|..:...|.|.:.:||.||..|.|.||...|.:
Human    27 VGGFTLGLSLATAYGLLELLVEGHSPWGCLVGTLTLAAFLSLGMGFSRQVRATVLLLLPQAFSRQ 91

  Fly    83 GRAFLISLAFVIAAVGPTANILANLKVMLRSLACGQELLRQALGQMLDVILEPVNAIQLAVDLLM 147
            ||..|:..||.:...||.||.|.|......::|||.||......::|....:|:.:....:..:.
Human    92 GRTLLLVAAFGLVLQGPCANTLRNFTRASEAVACGAELALNQTAEVLQRAKQPLVSALNKIKAIA 156

  Fly   148 REVRRVLKLAMVVLLRIQDQLIAIIKTLKNCAAWLKSIVDLCNTEMGTPWARCKKTAHHAMIRCQ 212
            |:.:.|..........|.|.:..|.:.|:|...||..|.|:||:|:|.|:.:|.:....|...|.
Human   157 RKTKEVADRVRKFFRSIMDGVKHIARALRNVWQWLLHIGDVCNSELGNPYLKCARVFDDAKDSCM 221

  Fly   213 SKMGVFKALCHAAKLF-LALCYPAKIIDVFCSGYWDLSWGLLDKIAERYREFVRHIEEMFDANIT 276
            ..:.....||:....| ||||..|.::.|||.....:...|...|.....:.:..:.:.|:.|:|
Human   222 MVIPQAYHLCYVLMPFKLALCGLASLVQVFCVIPKYIQPFLRQTIGTPVIQLLNRVRQEFEFNMT 286

  Fly   277 FEHEFFFDTNSSKSLTDVGEEILQDINKRLSSFIFLSSFVDILCWVMVVTVFFKATIFYLRYMHS 341
            ..|.|..|.|:|:||:.|..::.:.::.:|.......:.:.....:::|.::.:|..:...|::.
Human   287 ATHHFSVDLNASRSLSQVAMDLHEAVSMKLHRVREALALMGFTTPLLLVLLYLQALFYRYCYLNW 351

  Fly   342 RQFQNVFLTKILSDIDRRHEKHGYDPLLPLHQLERAKYMKLTSLRLTLFE-FVSIVENACFMATT 405
            ..:.|:::|.....::......|...:|||...|..:|:...|:.|:.:| |..|:|....:...
Human   352 DHYDNIYITSRFLRMEAVRSTAGLPTVLPLSAHEARRYIPPGSIFLSQWEKFFYILETFNLIRHL 416

  Fly   406 CLQLFAICFLDYGLFWLLATISLHGHQETGLEV---PAYVDLEIKGGGFVADVMRGIANAFRPLT 467
            .|.||.: ||||.:||:|   .|..||..|..|   |..|.|.::|.|:..::.|.:.:||..|.
Human   417 LLVLFLV-FLDYAVFWVL---DLARHQLQGEIVARSPVLVSLTVEGTGYAGNIYRDLVSAFDVLQ 477

  Fly   468 QKSILDVN-PCLPLPVKPDYAEYLIILLLCLLAWLILLAEPYILRTRHLIMAHFYPKRAKERGMF 531
            |.:|..:: .||..|.:||...|::|.::..|.:.|.|...|:.|.|.:|.|.:||.|.:||..:
Human   478 QGNISILSRRCLLRPSEPDSTGYIVIGVMYGLCFFITLFGSYVSRLRRVICASYYPSREQERISY 542

  Fly   532 LYNMISEDRTSIF----KFIRRRKRNEFNHTRNVKHTRNYTWLNNRFSCLMCMCSCCSSCQS--- 589
            |||::...||::.    :.:|||..:: .|             .:.|..|...|.|.....|
Human   543 LYNVLLSRRTNLLAALHRSVRRRAADQ-GH-------------RSAFLVLASRCPCLGPFVSHFW 593

  Fly   590 --TERCTICGRSL---TLSNRNPCDTPGCKGVYCGKCFEKSHNKCCLCNRPVDY-GDFSDVTEVD 648
              ...|..||:..   .:.|...|.||||:|:||..||....|.|.:|..|:.| ||..  .|:|
Human   594 LHQAYCLGCGQPQDEGDMENTVSCSTPGCQGLYCLTCFRLLDNTCSVCASPLSYQGDLD--LELD 656

  Fly   649 DSSD 652
            .|.:
Human   657 SSDE 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6845	NP_612000.3	DC_STAMP	344..533	CDD:462265	60/193 (31%)
DCST2	NP_653223.2	DC_STAMP	354..544	CDD:462265	60/193 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	692..773