Protein Alignment Pdk1 and pdpk1

DIOPT Version :9

• Sequence 1: NP_001261183.1
• Gene: Pdk1 / 38017
• FlyBaseID: FBgn0020386
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: XP_002938460.2
• Gene: pdpk1 / 779524
• XenbaseID: XB-GENE-991549
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 246/584 - (42%)
• Similarity: 328/584 - (56%)
• Gaps: 123/584 - (21%)

  Fly   206 YQSQQQQQQPQQQQEQQQQQEQSQQQQQLQNPAPRRS-PNDFIFGRYIGEGSYSIVYLAVDIHSR 269
            :..||:||.|||                     ||:. |.||.||:.:||||:|.|.||.::.:.
 Frog    15 HPGQQEQQHPQQ---------------------PRKKRPQDFKFGKILGEGSFSTVVLAKELTTG 58

  Fly   270 REYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLP 334
            ||||:|:.:||.|::|.|..|:.||::||.::.: |.||.|..||||...|||.::||:.|::|.
 Frog    59 REYAVKILQKRHIMKENKVQYVNREKDVMSRLDH-PFFVKLYFTFQDPEKLYFGLSYAKNGELLK 122

  Fly   335 YINRVGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHE 399
            ||.::||||..|||.|.||::.|.|::|...::|||||||||||.||||..|.|||:|||.::.
 Frog   123 YIRKIGSFDETCTRFYTAEIVCALEYLHENGIIHRDLKPENILLSEDMHIQITDFGTAKVSSSD- 186

  Fly   400 RALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNR 464
                    |:|.|:|
 Frog   187 --------SKQVRAN-------------------------------------------------- 193

  Fly   465 HRKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDF 529
                ||||||||||||:|.......::|||||||||||::|||||||..|:|:||::|:....||
 Frog   194 ----SFVGTAQYVSPELLTEKSACKSSDLWALGCIVYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 254

  Fly   530 PQGFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPPIYPYLPGV 594
            |:.|...|:|||.|||.:||..|||. :|.|.|..::|||||..:.||.|..||||.:..|||.:
 Frog   255 PEKFFPKAKDLVEKLLVIDPTKRLGC-EELGGYGPLKAHPFFETVTWQDLHLQTPPKLTAYLPAM 318

  Fly   595 SQ-DEDFRSSY----------------TVP--GDLEPGLDERQISRLLSAELGVGSSVAMPVKRS 640
            |: |||...:|                :.|  ..|||.|.:|           .||::...: ..
 Frog   319 SEDDEDCYGNYDDLLSQFGCMQVATSASSPSLAPLEPLLSQR-----------CGSNIEQYI-HD 371

  Fly   641 TAKNSFDL----NDAEKLQRLEQQ-KTDKWHVFADGEVILKKGFVNKRKGLFARKRMLLLTTGPR 700
            ...|||:|    ::|||...||:| ..::||.|.:..:|:|.|.|:||||||||:|.||||.||.
 Frog   372 LDNNSFELDLQFSEAEKRLLLEKQVGGNQWHQFVENNLIVKMGPVDKRKGLFARRRQLLLTEGPH 436

  Fly   701 LIYIDPVQMIKKGEIPWSPDLRAEYKNFKIFFVHTPNRTYYLDDPEGYAIHWSEAIENMRKLAY 764
            |.|:|||..:.|||||||.:||.|.||||.||||||||||||.||.|.|..|.:.|:.:.:..|
 Frog   437 LYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKKIQEVWRHRY 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk1	NP_001261183.1	STKc_PDK1	244..571	CDD:270733	141/326 (43%)
		S_TKc	246..571	CDD:214567	140/324 (43%)
		PH_PDK1	658..764	CDD:241293	61/106 (58%)
pdpk1	XP_002938460.2	STKc_PDK1	33..295	CDD:270733	141/326 (43%)
		PH_PDK1	394..500	CDD:241293	60/105 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5166
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37643
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1688
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1157543at2759
OrthoFinder	1	1.000	-	-		FOG0001781
OrthoInspector	1	1.000	-	-		oto103177
Panther	1	1.100	-	-	LDO	PTHR24356
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2717
SonicParanoid	1	1.000	-	-		X1315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190