Protein Alignment Pdk1 and Stk36

DIOPT Version :10

• Sequence 1: NP_728471.2
• Gene: Pdk1 / 38017
• FlyBaseID: FBgn0020386
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_778196.2
• Gene: Stk36 / 269209
• MGIID: 1920831
• Length: 1316
• Species: Mus musculus
• Alignment Length: 525
• Identity: 113/525 - (21%)
• Similarity: 198/525 - (37%)
• Gaps: 145/525 - (27%)

  Fly   252 IGEGSYSIVYLAVDIHSRREYAIKVCEKRLILR----ERKQDYIKREREVMHQMTNVPGFVNLSC 312
            |||||:..||     ..|::|:.:|...:.|.:    |::...::||.|:|..:.: |..|::..
Mouse    10 IGEGSFGRVY-----KGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWH-PNIVHMLD 68

  Fly   313 TFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENIL 377
            :|:..:.:..|..|| :|::...:...|.......:..||:|:.|..::|...::|||:||:|||
Mouse    69 SFETDKEVVVVTDYA-EGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNIL 132

  Fly   378 LDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDD 442
            |.:.....:.|||.|:.|:.:...|
Mouse   133 LAKGGGIKLCDFGFARAMSTNTMVL---------------------------------------- 157

  Fly   443 GDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGL 507
                                     .|..||..|:|||:::..|....||||::|||:|::..|.
Mouse   158 -------------------------TSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGT 197

  Fly   508 PPFRGSNDYVIFKEILDCAVDFPQGFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFF- 571
            |||..::.:.:...||...|.:|.......::.::.||..|||.||...|       :..|||.
Mouse   198 PPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPD-------LLHHPFIA 255

  Fly   572 ---------AGIDWQT-LRQQTPPPI--------YPYLPGVSQDEDFRSSYTVPGDLEPGLDERQ 618
                     ||.|..| ...:.||.:        :...|..:|....|.:..:..:.....:::.
Mouse   256 GRVTIITEPAGSDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILRQACKLMAEEAKQKEDQN 320

  Fly   619 ISRLLSAELGV----GSSVAMPVKRSTAKNSFDLNDAEKLQRLEQQKTDKWHVFADGE------- 672
            ....|..|.|:    .|:..:|..::|.:.|..|...     |..:..:.|..:..||
Mouse   321 AGSALEQEDGLCKVTPSTAPVPGLKATPQESSLLAGI-----LASEMKNNWEDWGAGEAPRTSRE 380

  Fly   673 ----VILKKGFVNKRKGLFARK------------------RMLLLTTGPRLIYIDPVQMIKKGEI 715
                :..::||...|.....|:                  :.||.|:.|     .|||:.....:
Mouse   381 NHINLECEQGFPEPRPEAMGRQSTDVVDPENEEPDSDDEWQRLLETSEP-----GPVQLKSPLTL 440

  Fly   716 PWSPD 720
            ..:||
Mouse   441 LCNPD 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk1	NP_728471.2	STKc_PDK1	244..571	CDD:270733	78/322 (24%)
		PH_PDK1	658..764	CDD:241293	16/92 (17%)
Stk36	NP_778196.2	STKc_STK36	2..254	CDD:270904	78/322 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..418		4/28 (14%)