Protein Alignment Pdk1 and ksg1

DIOPT Version :9

• Sequence 1: NP_001261183.1
• Gene: Pdk1 / 38017
• FlyBaseID: FBgn0020386
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_588442.1
• Gene: ksg1 / 2539517
• PomBaseID: SPCC576.15c
• Length: 592
• Species: Schizosaccharomyces pombe
• Alignment Length: 751
• Identity: 209/751 - (27%)
• Similarity: 316/751 - (42%)
• Gaps: 235/751 - (31%)

  Fly    78 TEATMPAMAKEKASATVSLGESNFRDINLKDLAVVVEAASRLHHQQNVCGCGAVSSTENNNNSRY 142
            |||:..|....::.:.:|....:...:|...|.....:|.   .|.|     |:::|.|.:.|:.
pombe    10 TEASEDAENDTQSESDLSFDHGSSEKLNRASLPKTQNSAI---PQSN-----ALNTTPNESTSQI 66

  Fly   143 GSSKYLTNG--HTSPLAAAVASNSSSVATTPHCRMLHNCSLQQYQNDIRQQTEILDMLRQQHQQG 205
            .||..:.:.  |.|      ..|.||.|:||:.:.:
pombe    67 DSSPKIPSAVPHIS------TPNPSSGASTPNIKRV----------------------------- 96

  Fly   206 YQSQQQQQQPQQQQEQQQQQEQSQQQQQLQNPAPRRSPNDFIFGRYIGEGSYSIVYLAVDIHSRR 270
                                                  :||.||..:||||||.|..|.:..::|
pombe    97 --------------------------------------SDFKFGEILGEGSYSTVLTATENSTKR 123

  Fly   271 EYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPY 335
            ||||||.:||.|::|:|:.|:..|:|.:..::..|||:.|..||||..:||||::.||.|::|.|
pombe   124 EYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDY 188

  Fly   336 INRVGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHER 400
            ||::|.|:..|.::|||.::.:.::||.|.|:||||||||||||::|.|.|.||||||::
pombe   189 INKLGRFNEICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKIL----- 248

  Fly   401 ALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRH 465
                         ||..                         |..|:.....|.|:...|
pombe   249 -------------NSSH-------------------------GSHEEDTHHADKPQAHSR----- 270

  Fly   466 RKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFP 530
               ||||||:|||||||.:.....|:|:||.|||::||:||.|||...|:|:.|:.||..:.:.|
pombe   271 ---SFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIP 332

  Fly   531 QGFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDW-QTLRQQTPPPIYPY---- 590
            ......|.||::|||.:||:|||..       :.|..||||.||.: .||.:..||.:.|:
pombe   333 PDISDVASDLIKKLLVLDPKDRLTV-------DEIHQHPFFNGIKFDNTLWELPPPRLKPFGHTS 390

  Fly   591 -----LPGVSQDEDFRSSYTVPGDLEPGLDERQISRLLSAELGVGSSVAMPVKRSTAK-NSFDLN 649
                 :|..|...:       .||             |::.|||.|.|:.....:.:. .:|:..
pombe   391 VLSLSVPNASNKHE-------NGD-------------LTSPLGVPSMVSASTNAAPSPVGTFNRG 435

  Fly   650 DAEKLQRLEQQKTDKW-HVFADGEVILKKGFVN---------------------KRKGLFARKRM 692
            .....|...:::..:| .:..|.|.|.|.|.:|                     |||     .|.
pombe   436 TLLPCQSNLEEENKEWSSILQDDEKISKIGTLNVYSMSGINGNDAFRFFSSLFRKRK-----PRT 495

  Fly   693 LLLTTGPRLIYID-------------PV-------QMIKKGEIPWSPDLRAEYKNFKIFFVHTPN 737
            .:||...|.:.:.             |:       :|:|..|..|              .|.||.
pombe   496 FILTNFGRYLCVASDGEGRKTVKEEIPIKSVGMRCRMVKNNEHGW--------------VVETPT 546

  Fly   738 RTYYLDDPEGYAIHWSEAIENMR--KLAYGDPSSTS 771
            :::..:||.|.|..|.|.::...  .|.:|:.|.||
pombe   547 KSWSFEDPNGPASAWVELLDKASSISLPFGNHSVTS 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk1	NP_001261183.1	STKc_PDK1	244..571	CDD:270733	131/326 (40%)
		S_TKc	246..571	CDD:214567	130/324 (40%)
		PH_PDK1	658..764	CDD:241293	29/149 (19%)
ksg1	NP_588442.1	STKc_PDK1	97..366	CDD:270733	131/326 (40%)
		S_TKc	99..366	CDD:214567	130/324 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0592
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	264	1.000	Inparanoid score	I736
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001781
OrthoInspector	1	1.000	-	-		otm47171
orthoMCL	1	0.900	-	-		OOG6_101713
Panther	1	1.100	-	-	LDO	PTHR24356
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2717
SonicParanoid	1	1.000	-	-		X1315
TreeFam	1	0.960	-	-
	10	9.850