Protein Alignment Pdk1 and sax-1

DIOPT Version :10

• Sequence 1: NP_728471.2
• Gene: Pdk1 / 38017
• FlyBaseID: FBgn0020386
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_508627.5
• Gene: sax-1 / 180655
• WormBaseID: WBGene00004727
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 469
• Identity: 116/469 - (24%)
• Similarity: 210/469 - (44%)
• Gaps: 83/469 - (17%)

  Fly   217 QQQEQQQQQEQSQQQQQLQNPAPRRSPNDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRL 281
            :::|::::...|::...|:....|.:.|||...:.||.|::..|.|.....:...||:|:..|..
 Worm    58 EEKEEKRKIHHSKETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSE 122

  Fly   282 ILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVAC 346
            ::.:.:..:::.||:::.: .:....|.:..:|||..:||.||.:...|||:..:.:..:.....
 Worm   123 MVEKEQTAHVRAERDILSE-ADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEA 186

  Fly   347 TRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQR 411
            |:.|.||..||.:.:|....:|||:||:|:|||...|..::|||   :.|..::...|:|   .|
 Worm   187 TQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFG---LCTGLKKFHRTDH---YR 245

  Fly   412 RSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKA---SFVGT 473
            ...|           ....||..:..|.                :.:...:.|:|:|   |.|||
 Worm   246 NWPS-----------TLPPDFISKPFES----------------KRKAETWKRNRRAYAYSTVGT 283

  Fly   474 AQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDC--AVDFPQG--FD 534
            ..|::|||.|....|.:.|.|:||.|:|:|:.|.|||........::::::.  .:.||..  ..
 Worm   284 PDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPIS 348

  Fly   535 KDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPPIYPYLPGVSQ--- 596
            .:|:..:::.. .:...|||   ..|..:.|:..||...|||..:|:: ||||...:..:..
 Worm   349 IEAKATIKRFC-CEAERRLG---NHGGLDEIKQCPFVKRIDWNHIRER-PPPIRVTVKSIDDTSN 408

  Fly   597 -----DED--FRSSYTVPGDLEPGLDERQISRLLSAELGVGSSVAMPVKRSTAKNSFD------- 647
                 |||  :.:|..:..:.:||   |:           |..|....||      ||
 Worm   409 FDDFPDEDLTWPTSTLIRPEEQPG---RR-----------GEFVDFTYKR------FDGLTQKMR 453

  Fly   648 LNDAEKLQRLEQQK 661
            .:|.:|.|:.::.|
 Worm   454 YSDLKKFQQAKKNK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdk1	NP_728471.2	STKc_PDK1	244..571	CDD:270733	86/333 (26%)
		PH_PDK1	658..764	CDD:241293	1/4 (25%)
sax-1	NP_508627.5	MobB_NDR-like	18..82	CDD:439270	3/23 (13%)
		STKc_NDR_like	85..443	CDD:270750	104/410 (25%)