DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lsp1gamma and CG8100

DIOPT Version :9

Sequence 1:	NP_523868.1	Gene:	Lsp1gamma / 38015	FlyBaseID:	FBgn0002564	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_001261825.1	Gene:	CG8100 / 39565	FlyBaseID:	FBgn0036410	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	782	Identity:	169/782 - (21%)
Similarity:	286/782 - (36%)	Gaps:	229/782 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLTLVILALVAC---VTAFSVP-----TQKVKIADKNFLEKQKFLFEIVHRIDEPLMFEEWIKM 57
            ::||.|.|..:..   ..:|..|     :..|::......::|.||..::.::.:||:.||.|.|
  Fly     2 LRLTFVCLCFLVLQNRTESFGSPWKYFGSSNVEVNYNQRQDRQYFLLNLLIQVHKPLLHEELITM 66

  Fly    58 GQKLITDKAQYETFDFYMEKLWESYKLGALLPKGEFFGALVKTHHKQA----------------- 105
            |.:|..|.      |.|.|..|...|        :|   ..:.|..:.
  Fly    67 GSQLNDDP------DSYKEGTWRYIK--------DF---RERVHQNRVPGPFVILNQLDEEMPLN 114

  Fly   106 -YGLFNFFYYAKDWETFVRNVAWARIHVNEGMFVYALTLAVIHKPEFEGLILPQIYEIFPQYFFN 169
             .|::.|...|.||.:|.||..:||||.:..:||.||.:||..:.:.:.|.:|.:||:.||.:|.
  Fly   115 LLGIYRFLTMAVDWTSFQRNACFARIHFHPLLFVNALQMAVEEREDTKDLRMPAMYEVLPQLYFE 179

  Fly   170 SKFVYAAEKFDYEVFS--KLTMYEKEYKDIL--YKDYSEFTGNFYFYTKDWKTWQWYKMMGLDQE 230
            .:.:..|::..:...|  :|...::.:.|||  |::..                         |.
  Fly   180 KEVILTAQEVTWNQLSPIRLVTPKRRWIDILLGYRNPK-------------------------QP 219

  Fly   231 WYVEDKYFLRENLSQFVNDPKYVDVVKGLKKFYMPVDYTRDIDFFNDETKMTYFTEDLGWNAYWY 295
            |..|:         ....||..:|                      :..|:.|.:.||..|::|.
  Fly   220 WMEEE---------PIPTDPLIID----------------------NARKVAYLSLDLELNSHWN 253

  Fly   296 YLNMDYAFFL-NGKQ-----FGLDKDR----RGEY--------------------WIYNVQQILA 330
            .|.......: .||:     ..:|.||    ||.:                    ::||:.|.:|
  Fly   254 SLITRLIISIEEGKEKTNEPIIIDGDRLVAFRGSFDEVNFKKHLALGSHFHNTKLYLYNLHQFVA 318

  Fly   331 RYYQERLANGFGEIPEFFWYKQIEYGYDPQL----IYYNGIGYSYR--KNYYDFYTYG---KFEM 386
            ....|.||.|         .|..|..|.|.:    :.|.|...:..  :...|....|   |.||
  Fly   319 ALSMEDLATG---------QKSTELIYPPLMTTGGVPYKGTSLNIEAVRGIIDLTIDGLKDKIEM 374

  Fly   387 YSQIQNFFSRVYKVLETGFYKTADGQVFDLHKPEAIKIVGNYLQGNADTFDKYFFNYYYLLAHMY 451
            ..:..|                        |..:.:.|.|..: ||         ||.::...:.
  Fly   375 AVKHNN------------------------HAMDNLSIAGGII-GN---------NYLHICRQLN 405

  Fly   452 FADVDYNDMEV-FPNVFLNFETMLRDPFFYTFYKKFTDVFYTFKYYLKPYTQKDLF-----YEGI 510
            .|   .|...: .|::..:..:.||||.:.:...:..|:       ||.|..:::|     .|..
  Fly   406 LA---VNGQGINQPSMLGSATSNLRDPIYRSLLFRIYDL-------LKSYENENIFPDVGGRETP 460

  Fly   511 TIKDVSVSKLVTYYDIVDFDVTNLLNDKMTFV---DGQYIWDKALLARQARLNHKPFNFEFTIDS 572
            .|.|:.||:|||:.:.:..|:.||::.::...   :.|:: .:.|:|||.||||.||:....|.:
  Fly   461 KIVDIQVSRLVTFEETMTTDLINLIDQQLLLSHRNNLQFL-RRNLVARQHRLNHDPFSIGLDIVA 524

  Fly   573 DKVQKGVVRVFLGPKFDEYGRVIPLDYNRKNFVQIDSFVYPFIAGTNTIKRSSKEFSWTAEDRIT 637
            .:......|::|.         :|.....:  :.:|||......|.|..:|   :|. ||..:.|
  Fly   525 PENLVVEARMYLS---------LPNQLRLR--LHLDSFKCSLKRGLNHFER---QFP-TAISKPT 574

  Fly   638 YTELYKYVMLASEGKYDFPLDISEPHNAFPDRLVLPKGWEQGMPMQFYFFVSPFAETYEQFSNFD 702
            .:|||         :.|:........|.||..|.||:|...|:.:|....:|.:......|....
  Fly   575 LSELY---------EADYASTDVTTSNRFPPHLQLPRGTGDGLKLQLLVELSEWNGLESHFDGAS 630

  Fly   703 YT 704
            .|
  Fly   631 VT 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsp1gamma	NP_523868.1	Hemocyanin_N	31..153	CDD:397678	37/139 (27%)
		Hemocyanin_M	159..490	CDD:395296	67/374 (18%)
		Hemocyanin_C	499..747	CDD:397679	54/214 (25%)
CG8100	NP_001261825.1	Hemocyanin_N	41..163	CDD:281684	37/138 (27%)
CG8100	NP_001261825.1	Hemocyanin_C	444..>621	CDD:281685	52/201 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470647
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IXN
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0012705
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840