DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lsp1gamma and Lsp1beta

DIOPT Version :9

Sequence 1:	NP_523868.1	Gene:	Lsp1gamma / 38015	FlyBaseID:	FBgn0002564	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_001285556.1	Gene:	Lsp1beta / 33274	FlyBaseID:	FBgn0002563	Length:	789	Species:	Drosophila melanogaster

Alignment Length:	777	Identity:	485/777 - (62%)
Similarity:	610/777 - (78%)	Gaps:	8/777 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLTLVILALVACVTAFSV-PTQKVKIADKNFLEKQKFLFEIVHRIDEPLMFEEWIKMGQKLITD 64
            ||:.:.:||.:....|.|. .|.:||||||.||.|||||||||:|:::|||||:.||.|:|...:
  Fly     1 MKIAIALLACLGLAAAASFHQTHEVKIADKAFLMKQKFLFEIVYRVEDPLMFEDHIKQGEKFYFE 65

  Fly    65 KAQYETFDFYMEKLWESYKLGALLPKGEFFGALVKTHHKQAYGLFNFFYYAKDWETFVRNVAWAR 129
            ::.|..:|.||:|.:|:||..|||||||||||||.:|.|||.|||||||||||||||..||||||
  Fly    66 ESYYTHYDMYMKKFFEAYKAHALLPKGEFFGALVMSHAKQARGLFNFFYYAKDWETFAANVAWAR 130

  Fly   130 IHVNEGMFVYALTLAVIHKPEFEGLILPQIYEIFPQYFFNSKFVYAAEKFDYEVFSKLTMYEKEY 194
            :||||||||||||:||||:.:|.||:||.|||||||:|||||||:.|||||||::.|:|||||||
  Fly   131 MHVNEGMFVYALTMAVIHRNDFHGLMLPSIYEIFPQFFFNSKFVFEAEKFDYEMWMKMTMYEKEY 195

  Fly   195 KDILYK----DYSE-FTGNFYFYTKDWKTWQWYKMMGLDQEWYVEDKYFLRENLSQFVNDPKYVD 254
            .|:.||    |||. :..:.|.|.||:|||||:|:|||.:.||.|||:.||||:.:|..:.|::.
  Fly   196 MDVYYKTNGYDYSTMYRSSDYTYMKDFKTWQWWKLMGLGEHWYTEDKFILRENIYEFNQETKWLS 260

  Fly   255 VVKGLKKFYMPVDYTRDIDFFNDETKMTYFTEDLGWNAYWYYLNMDYAFFLNGKQFGLDKDRRGE 319
            ::|.:||||||||||||::.:|.|:|::|||||||||||||||||||:|||:|..|.|..|||||
  Fly   261 MMKDVKKFYMPVDYTRDLNLYNKESKLSYFTEDLGWNAYWYYLNMDYSFFLDGNTFDLKNDRRGE 325

  Fly   320 YWIYNVQQILARYYQERLANGFGEIPEFFWYKQIEYGYDPQLIYYNGIGYSYRKNYYDFYTYGKF 384
            :|:|||.|:|:|||.|||::||||||||.||:|||.|||||||||||||||:|||||:..||..:
  Fly   326 WWLYNVHQLLSRYYMERLSHGFGEIPEFSWYQQIEMGYDPQLIYYNGIGYSFRKNYYEMETYANY 390

  Fly   385 EMYSQIQNFFSRVYKVLETGFYKTADGQVFDLHKPEAIKIVGNYLQGNADTFDKYFFNYYYLLAH 449
            :|..:|..|..|::.::|.|:||||||...||.|||||:.:||.||||.|..||.|:.::|:|||
  Fly   391 DMLDKITGFLKRIHNIVEMGYYKTADGHTIDLRKPEAIEFIGNMLQGNVDAMDKMFYQFWYMLAH 455

  Fly   450 MYFADVDYNDMEVFPNVFLNFETMLRDPFFYTFYKKFTDVFYTFKYYLKPYTQKDLFYEGITIKD 514
            |||||.||..|:|:|||.||||||:|||.:|.|||....|::.|.:||..||::.|...|:|:|:
  Fly   456 MYFADADYYQMDVYPNVMLNFETMMRDPMYYMFYKSIAQVYFQFMHYLPKYTKEQLLMPGVTMKN 520

  Fly   515 VSVSKLVTYYDIVDFDVTNLLNDKMTFVDGQYIWDKALLARQARLNHKPFNFEFTIDSDKVQKGV 579
            |.||.|.||:|:|||||||:|||||.|.||:::||.:|.|||.|||||||.:.:||:|:||:|.|
  Fly   521 VEVSDLTTYFDLVDFDVTNMLNDKMIFQDGKFVWDMSLFARQMRLNHKPFTYTYTIESEKVEKVV 585

  Fly   580 VRVFLGPKFDEYGRVIPLDYNRKNFVQIDSFVYPFIAGTNTIKRSSKEFSWTAEDRITYTELYKY 644
            :|.||||||||:|:||.|..||.||::||.|.|...||||.|.|.|.||.||.:||.||||||.|
  Fly   586 IRAFLGPKFDEFGKVISLAENRMNFMEIDEFYYELKAGTNKITRKSSEFYWTVKDRTTYTELYYY 650

  Fly   645 VMLASEGKYDFPLDISEPHNAFPDRLVLPKGWEQGMPMQFYFFVSPF-AETYEQFSNFDYTYSSG 708
            .|:|.:|||||||||||||..||||||||.||::|||||.:|.|.|: |..:||||.||||||.|
  Fly   651 TMMAFDGKYDFPLDISEPHCGFPDRLVLPMGWQKGMPMQMFFMVVPYVAPAHEQFSTFDYTYSCG 715

  Fly   709 VGSGTRFVDTKPFGYPFDRQIDESDFFVPNGFFKDVKVYYVDTFAKYFE-KKYTQFGTFDYS 769
            :|||.|:||:.||||||||.|||.:|||||.:||||.:|:.||...|:: |.|:.:|.|||:
  Fly   716 IGSGARYVDSLPFGYPFDRAIDEYEFFVPNMYFKDVSIYHADTMEPYYKYKSYSNYGHFDYT 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsp1gamma	NP_523868.1	Hemocyanin_N	31..153	CDD:397678	84/121 (69%)
		Hemocyanin_M	159..490	CDD:395296	210/335 (63%)
		Hemocyanin_C	499..747	CDD:397679	160/248 (65%)
Lsp1beta	NP_001285556.1	Hemocyanin_N	32..154	CDD:281684	84/121 (69%)
		Hemocyanin_M	161..496	CDD:278784	209/334 (63%)
		Hemocyanin_C	505..755	CDD:281685	160/249 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IXN
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	554	1.000	Inparanoid score	I2689
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27073
OrthoDB	1	1.010	-	-		D130404at33208
OrthoFinder	1	1.000	-	-		FOG0012705
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3797
	9	8.910