DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lsp1gamma and Lsp1alpha

DIOPT Version :9

Sequence 1:	NP_523868.1	Gene:	Lsp1gamma / 38015	FlyBaseID:	FBgn0002564	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_511138.2	Gene:	Lsp1alpha / 32199	FlyBaseID:	FBgn0002562	Length:	816	Species:	Drosophila melanogaster

Alignment Length:	804	Identity:	474/804 - (58%)
Similarity:	603/804 - (75%)	Gaps:	35/804 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLTLVILALVACVTAFSV-PTQKVKIADKNFLEKQKFLFEIVHRIDEPLMFEEWIKMGQKLITD 64
            ||..:..||.||.|||.:. .|..:|:|||.||.|||||||||:|:::||||||:|.||::...|
  Fly     1 MKFAIAFLACVAVVTATAYHKTHDIKVADKAFLMKQKFLFEIVYRVEDPLMFEEYIAMGKQFYFD 65

  Fly    65 KAQYETFDFYMEKLWESYKLGALLPKGEFFGALVKTHHKQAYGLFNFFYYAKDWETFVRNVAWAR 129
            |..|..||.||||.:|::|..||||||||||||||.|.|||.|||||||||||||||:.|||:||
  Fly    66 KEHYTHFDLYMEKFFEAHKAHALLPKGEFFGALVKHHAKQARGLFNFFYYAKDWETFMTNVAFAR 130

  Fly   130 IHVNEGMFVYALTLAVIHKPEFEGLILPQIYEIFPQYFFNSKFVYAAEKFDYEVFSKLTMYEKEY 194
            :|.|||||||||||||||:.:|.||:||.|:|||||:|||||||..|||||||::.|.::|||||
  Fly   131 MHFNEGMFVYALTLAVIHRDDFHGLVLPAIHEIFPQFFFNSKFVMEAEKFDYEMWMKTSLYEKEY 195

  Fly   195 KDILYK--DYSEFTGNF------------------------------YFYTKDWKTWQWYKMMGL 227
            .|:.:|  .:|.:...:                              |.|.||:|||||:|:|||
  Fly   196 MDVYHKIPTFSSYEHGYKQGMAYGYGKTHGHGQTYEHEFGSMYQTSDYMYMKDFKTWQWWKLMGL 260

  Fly   228 DQEWYVEDKYFLRENLSQFVNDPKYVDVVKGLKKFYMPVDYTRDIDFFNDETKMTYFTEDLGWNA 292
            .:.||.|..|.||||:.::..:..::.::|.:|||||||||:||:..:|:|:|::|||||||||:
  Fly   261 GEHWYSESNYILRENIYEYNQESNWLTMMKDVKKFYMPVDYSRDLYLYNEESKLSYFTEDLGWNS 325

  Fly   293 YWYYLNMDYAFFLNGKQFGLDKDRRGEYWIYNVQQILARYYQERLANGFGEIPEFFWYKQIEYGY 357
            |||||||||:|||:||.|||..|||||:|:|||.|:|:||:.|||::|.||||:|.|:.|||.||
  Fly   326 YWYYLNMDYSFFLDGKTFGLQNDRRGEWWLYNVHQLLSRYHMERLSHGLGEIPQFSWFHQIEMGY 390

  Fly   358 DPQLIYYNGIGYSYRKNYYDFYTYGKFEMYSQIQNFFSRVYKVLETGFYKTADGQVFDLHKPEAI 422
            |||||||||||||||||||:..|||.|||..:|..|..|:..::|.|:|:|.||.:.||.|||:|
  Fly   391 DPQLIYYNGIGYSYRKNYYELETYGNFEMLDKITGFQQRIQNIVELGYYQTTDGHMIDLRKPESI 455

  Fly   423 KIVGNYLQGNADTFDKYFFNYYYLLAHMYFADVDYNDMEVFPNVFLNFETMLRDPFFYTFYKKFT 487
            :|:||.||||.|..|..||.::|:||||||||..|..|||:|||.||||||:|||.||.|||...
  Fly   456 EIIGNMLQGNVDAIDNIFFQFWYMLAHMYFADTHYYQMEVYPNVMLNFETMMRDPMFYMFYKSIA 520

  Fly   488 DVFYTFKYYLKPYTQKDLFYEGITIKDVSVSKLVTYYDIVDFDVTNLLNDKMTFVDGQYIWDKAL 552
            .|::.|.::|..||::.|...|:|:|.|.||:||||:|:|||||||:||.||.|.:||::|||:|
  Fly   521 QVYFQFMHHLPKYTKEQLLMPGVTLKHVEVSELVTYFDLVDFDVTNMLNGKMVFHEGQFLWDKSL 585

  Fly   553 LARQARLNHKPFNFEFTIDSDKVQKGVVRVFLGPKFDEYGRVIPLDYNRKNFVQIDSFVYPFIAG 617
            .|||.|||||||::.:||||.:.:|.|:|.|||||||||||:|.|..||.||::||.|.|....|
  Fly   586 FARQMRLNHKPFSYTYTIDSARDEKVVIRAFLGPKFDEYGRMISLTDNRMNFMEIDEFTYTLKTG 650

  Fly   618 TNTIKRSSKEFSWTAEDRITYTELYKYVMLASEGKYDFPLDISEPHNAFPDRLVLPKGWEQGMPM 682
            :|.|.|.|.:|:||.:||.||||||.|.|:|.:||||:|||::|||..||||||||.||::||||
  Fly   651 SNLITRKSTDFAWTVKDRTTYTELYYYTMMAFDGKYDYPLDLTEPHCGFPDRLVLPMGWKKGMPM 715

  Fly   683 QFYFFVSPF-AETYEQFSNFDYTYSSGVGSGTRFVDTKPFGYPFDRQIDESDFFVPNGFFKDVKV 746
            |.:|.|.|: |..:||||.||||||.|:|||.|.||:.||||||||:|:|.:|.|||.:||||.:
  Fly   716 QMFFMVVPYMAPQHEQFSTFDYTYSCGIGSGARHVDSLPFGYPFDREINEYEFHVPNMYFKDVTI 780

  Fly   747 YYVDTFAKYFE-KKYTQFGTFDYS 769
            |:.||..||:. |:||.:|.||||
  Fly   781 YHADTMEKYYNYKEYTNYGHFDYS 804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsp1gamma	NP_523868.1	Hemocyanin_N	31..153	CDD:397678	87/121 (72%)
		Hemocyanin_M	159..490	CDD:395296	200/362 (55%)
		Hemocyanin_C	499..747	CDD:397679	153/248 (62%)
Lsp1alpha	NP_511138.2	Hemocyanin_N	32..154	CDD:281684	87/121 (72%)
		Hemocyanin_M	287..523	CDD:278784	150/235 (64%)
		Hemocyanin_C	532..782	CDD:281685	153/249 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470634
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IXN
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	554	1.000	Inparanoid score	I2689
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27073
OrthoDB	1	1.010	-	-		D130404at33208
OrthoFinder	1	1.000	-	-		FOG0012705
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11511
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3797
	9	8.910