Protein Alignment mthl8 and mthl4

DIOPT Version :9

• Sequence 1: NP_001261182.1
• Gene: mthl8 / 38013
• FlyBaseID: FBgn0052475
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Alignment Length: 454
• Identity: 104/454 - (22%)
• Similarity: 187/454 - (41%)
• Gaps: 92/454 - (20%)

  Fly    30 CAFIDTANIT-------GSYGLDGPFVHNWTVIPRHFVAVYDF-VIENGIRIPASRHLRACVCKT 86
            |.|.||.:|:       |||..:|      .:||.|..|.||: ::.:..:...:.|:|.|.|..
  Fly    23 CDFFDTVDISKAPRFSNGSYLYEG------LLIPAHLTAEYDYKLLADDSKEKVASHVRGCACHL 81

  Fly    87 KPCVRICCLRGEIYDLEKRQCLVPVAGVSSLPSHS-HMEVELGNGSLRLVKLQPRFSIHVETP-- 148
            :||:|.||  .:...::|.:|...:: ...|..|. .:.|.|.:||  :|:...:..:.|::.
  Fly    82 RPCIRFCC--PQYQKMQKSKCYGDMS-EDELNKHDPFVNVTLSDGS--VVRRHFKEDLIVQSDLA 141

  Fly   149 ---CEHMKAVT---KGSEYVHWTLHENGTISH---RGHIFSKHYCFTPLLHGNSTWEWQPLACAP 204
               |..|..:.   .|:|:   ||.|||::..   :..:..:.||...|...:.:....|..|..
  Fly   142 KPGCPRMYFLNHELPGNEF---TLFENGSLLRHWDKVELSKREYCVQHLSFKDDSIRIAPHFCPL 203

  Fly   205 EKLYFVLGVREWTYAICLLIAILSMFIVLMVYLMCSEMRNSFYGVAIKAYAICMILGYALLAYLT 269
            ...:    .|.|. .:.::|:::.:.:.:.|||...::|| .:|.....|...:.|||..|..
  Fly   204 SSEH----SRTWK-TVAIVISLICIILTISVYLYVEKLRN-LHGKCFICYLASLFLGYFFLVL-- 260

  Fly   270 LHNPANLSNAACRILPSLALMNLVLSFYILSFIAFKLYLSF------------------YGVVFT 316
              |....|:..|.....|...:::.:|:.||.|...|.:.|                  |
  Fly   261 --NVWKYSSGFCVTAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAY----- 318

  Fly   317 KLMFWLIFTPIVLVAVGWSFFVGFSYYGSRLIFG---------GDTCWFDPRNWSVMIYFYAPVF 372
            .|..|.|  |:::.|:        :|...:::..         |..||....:.:||||||.|:.
  Fly   319 NLYAWGI--PLIMTAI--------TYTADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPML 373

  Fly   373 VACAISGFFYVLSQIYIRD-----QPDIETEKSFESI-EKNRFKSFWKYFGYTAVVWVVCICSF 430
            :..|.:...:|||.|||.:     :..:..:::.:.| ::..|..|.:.|....:.|...|.||
  Fly   374 LLIAFNIIMFVLSAIYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSF 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl8	NP_001261182.1	Methuselah_N	30..202	CDD:284145	47/191 (25%)
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	47/191 (25%)
		7tm_4	213..>385	CDD:304433	40/191 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020