DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl8 and Dh44-R2

DIOPT Version :9

Sequence 1:NP_001261182.1 Gene:mthl8 / 38013 FlyBaseID:FBgn0052475 Length:492 Species:Drosophila melanogaster
Sequence 2:NP_610789.3 Gene:Dh44-R2 / 36368 FlyBaseID:FBgn0033744 Length:476 Species:Drosophila melanogaster


Alignment Length:415 Identity:77/415 - (18%)
Similarity:135/415 - (32%) Gaps:133/415 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   127 LGNGSLRLVKLQPRF------------SIHVETPC-EHMKAVTKGSEYVHWTLHENGTISHRGHI 178
            |.:|..|:::....|            |:.| .|| |..|.       ||:...:|.|       
  Fly    74 LASGGKRILQCPSSFDSVLCWPRTNAGSLAV-LPCFEEFKG-------VHYDTTDNAT------- 123

  Fly   179 FSKHYCFTPLLHGNSTW--------------------EWQPLACAPEKLYFVLGVREWTYAICLL 223
               .:||.     |.||                    ::.|....|..:          ||....
  Fly   124 ---RFCFP-----NGTWDHYSDYDRCHQNSGSIPVVPDFSPNVELPAII----------YAGGYF 170

  Fly   224 IAILSMFIVLMVYLMCSE---MRNSFYGVAIKAY---AICMILGYALLAYLTLHNPAN------- 275
            ::..::.:.|:::|...:   :||:.:......|   |:..||...|....|..:.|.       
  Fly   171 LSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLVIM 235

  Fly   276 -----LSNAACRILPSLALMNLVLSFYILSFIAFKLYLSFYGVVFTKLMFWLIFTPIVLVAVGWS 335
                 |:|.....:..|.|..||:..:....|:|.:|         .|:.|  ..|.|.:.| ||
  Fly   236 FQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIY---------ALIGW--GCPAVCILV-WS 288

  Fly   336 FFVGFSYYGSRLIFGG---DTCWFDPRNWSVMIYFYAPVFVACAISGFFYV-LSQIYI---RDQP 393
            ....|:.:.....|.|   |..|.  |...:...|..|..:|..::..|.: :..:.|   |...
  Fly   289 IAKAFAPHLENEHFNGLEIDCAWM--RESHIDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAH 351

  Fly   394 DIETEKSFESIEKNRFKSFWKYFGYTAVVWVVCICSFAFNYYWE--------NRSHLNYAVSFCM 450
            .:||.:.:::                :...:|.|..|...|...        :|:......:|.:
  Fly   352 TLETRQYYKA----------------SKALLVLIPLFGITYLLVLTGPEQGISRNLFEAIRAFLI 400

  Fly   451 AFHGF--AALYALIGKNQQIQNFLR 473
            :..||  |..|..:  |.:::..||
  Fly   401 STQGFFVALFYCFL--NSEVRQTLR 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl8NP_001261182.1 Methuselah_N 30..202 CDD:284145 20/107 (19%)
Dh44-R2NP_610789.3 HRM 82..144 CDD:280888 16/84 (19%)
7tm_2 159..407 CDD:278432 52/287 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45462203
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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