DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl8 and adgre14

DIOPT Version :9

Sequence 1:NP_001261182.1 Gene:mthl8 / 38013 FlyBaseID:FBgn0052475 Length:492 Species:Drosophila melanogaster
Sequence 2:XP_021330419.1 Gene:adgre14 / 108182849 ZFINID:ZDB-GENE-131120-49 Length:505 Species:Danio rerio


Alignment Length:323 Identity:65/323 - (20%)
Similarity:116/323 - (35%) Gaps:85/323 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   205 EKLYFVLGVREWTYAICLLIAILSMFIVLMVYLMCSEMRNSFYGVAIKAYA---ICMILGYALLA 266
            :.|..||.|      :|:::.:|...:.|:.:..|.      :...:...|   ||:.|..|.|.
Zfish   214 DSLLNVLNV------VCVIVGLLFFSLALLTFTRCQ------WSPGVNNVARINICISLLLAHLL 266

  Fly   267 YLTLHNPANL---SNAACRILPSLALMNLVLSFYILSFI-AFKLYL----------SFYGVVFTK 317
            :|......:|   ....|.::..| |..|.||.::..|| |..|::          ....|:..|
Zfish   267 FLLTQQFLSLIRRQKVLCMLISGL-LHFLFLSGFVWMFIEAVLLFICVKNLSQISSQMKNVLRNK 330

  Fly   318 LMFWLIFTPIVLVAVGWSFFVGFSYYGSRLIFGGDTCWFDPRN---WSVMIYFYAPVFVACAISG 379
            |: .:|...:.||.|..|..|..:.|||      :.||.....   ||    |..||.:..|::.
Zfish   331 LL-CVIGYAVALVVVSISAAVVPNGYGS------EKCWIQMHKGFIWS----FLGPVTIIIALNV 384

  Fly   380 FFYV-----LSQIYIRDQPDIETEKSFESIEKNRFKSFWKYFGYTAVVWVVCICSFAFNYYWENR 439
            ..::     |...:.:...|:      ..:.:.:...|     .|...:||..||:...::..:.
Zfish   385 ILFISIGFSLKSAFKKLNADV------SQLNQTKIVMF-----KTLAQFVVLGCSWILGFFTNSS 438

  Fly   440 SHLNYA-------------VSFCMAFHG--------FAALYALIGKNQQIQNFLRRIDNGEDT 481
            ..|...             :.:|:...|        |.:||:    ..:.:||....:|.||:
Zfish   439 KVLEILFLILNSQQGTFIFLIYCVLNKGIRQEYRKLFTSLYS----GLKPKNFNWSSENTEDS 497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl8NP_001261182.1 Methuselah_N 30..202 CDD:284145
adgre14XP_021330419.1 GPS 167..205 CDD:197639
7tm_GPCRs 214..476 CDD:333717 57/296 (19%)
TM helix 1 217..241 CDD:320095 6/29 (21%)
TM helix 2 250..271 CDD:320095 7/20 (35%)
TM helix 3 285..307 CDD:320095 7/22 (32%)
TM helix 4 331..347 CDD:320095 5/16 (31%)
TM helix 5 365..388 CDD:320095 6/26 (23%)
TM helix 6 412..435 CDD:320095 6/27 (22%)
TM helix 7 439..464 CDD:320095 2/24 (8%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1153592at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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