DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl8 and LOC103911493

DIOPT Version :9

Sequence 1:NP_001261182.1 Gene:mthl8 / 38013 FlyBaseID:FBgn0052475 Length:492 Species:Drosophila melanogaster
Sequence 2:XP_021326603.1 Gene:LOC103911493 / 103911493 -ID:- Length:301 Species:Danio rerio


Alignment Length:286 Identity:66/286 - (23%)
Similarity:107/286 - (37%) Gaps:53/286 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   195 WEWQPLACAPEKLYFVLGVREWTYAICLLIAI---LSMFIVLMVYLMCSEMRNSFYGVAIKAYA- 255
            |...|.|.|         |..:..::.|:.::   :|:|.:.:...|...:|.:....|.|... 
Zfish     2 WNSVPDASA---------VAPYLDSLTLISSVGCGISVFFLAIALFMHFLLRKAKSNQATKILIN 57

  Fly   256 ICMILGYALLAYLTLHNPANLSNA-ACRILPSLALMNLVLSF--YILSFIAFKLYLSFYGVVFTK 317
            |.:.|.:..:::|:..:.||..:. ||..:..|...:::.:|  :.:..:...|:|....|..|.
Zfish    58 ILVALFFLNVSFLSNESVANSGDKNACVFIALLMHYSMLTTFTWFFIQALHMYLWLIRQNVTITN 122

  Fly   318 LM------FWLIFTPIVLVAVGWSFFVGFSYYGSRLIFGGDT-------CWFDPR--NWSVMIYF 367
            .|      .|.:..||| |||       .|..|.:.:....|       ||....  .:.|.|.|
Zfish   123 YMRKITVLGWGVSMPIV-VAV-------LSTGGYKAVTLSSTSGKIARMCWITDLFIQYIVNIGF 179

  Fly   368 YAPVFVACAISGFFYVLSQIYIRDQPDIE-TEKSFESIEKNRFK--SFWKYFGYTAVVWVVCICS 429
            |:.||:...|   .:::|...|....||. ||....:..|....  |.:..||.|   |.|    
Zfish   180 YSLVFIFTTI---IFIISVTNIFQSRDIRATEGKRLTFRKQLMMVLSLFFLFGLT---WAV---- 234

  Fly   430 FAFNYYWENRSHLNYAVSFCMAFHGF 455
             ||..|........|..|...:|.||
Zfish   235 -AFFSYGPMLIPSYYIFSVLNSFQGF 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl8NP_001261182.1 Methuselah_N 30..202 CDD:284145 2/6 (33%)
LOC103911493XP_021326603.1 7tm_GPCRs 18..265 CDD:333717 61/261 (23%)
TM helix 1 18..42 CDD:320095 4/23 (17%)
TM helix 2 52..73 CDD:320095 4/20 (20%)
TM helix 3 85..107 CDD:320095 2/21 (10%)
TM helix 4 126..142 CDD:320095 5/16 (31%)
TM helix 5 169..192 CDD:320095 7/25 (28%)
TM helix 6 215..240 CDD:320095 9/32 (28%)
TM helix 7 244..265 CDD:320095 5/16 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1153592at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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