Protein Alignment mthl8 and LOC103911493

DIOPT Version :10

• Sequence 1: NP_611998.1
• Gene: mthl8 / 38013
• FlyBaseID: FBgn0052475
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_068073930.2
• Gene: LOC103911493 / 103911493
• -ID: -
• Length: 505
• Species: Danio rerio
• Alignment Length: 309
• Identity: 67/309 - (21%)
• Similarity: 114/309 - (36%)
• Gaps: 61/309 - (19%)

  Fly   191 GNSTWEWQPLACAPEKL-------------YFVL--------GVREWTYAICLLIAI---LSMFI 231
            ||...||....|..|.:             :|.:        .|..:..::.|:.::   :|:|.
Zfish   172 GNGNLEWTTFGCETEMIDNNTIKCSCSHLTFFAVLMSVPDASAVAPYLDSLTLISSVGCGISVFF 236

  Fly   232 VLMVYLMCSEMRNSFYGVAIKAYAICMILGYAL-LAYLTLHNPANLSNA-ACRILPSLALMNLVL 294
            :.:...|...:|.:....|.|.....::..:.| :::|:..:.||..:. ||..:..|...:::.
Zfish   237 LAIALFMHFLLRKAKSNQATKILINILVALFLLNVSFLSNESVANSGDKNACVFIALLMHYSMLT 301

  Fly   295 SF--YILSFIAFKLYLSFYGVVFTKLM------FWLIFTPIVLVAVGWSFFVGFSYYGSRLIFGG 351
            ||  :.:..:...|:|....|..|..|      .|.:..||| |||       .|..|.:.:...
Zfish   302 SFTWFFIQALHMYLWLIRQNVTITNYMRKITVLGWGVSMPIV-VAV-------LSTGGYKAVTLS 358

  Fly   352 DT-------CWFDPR--NWSVMIYFYAPVFVACAISGFFYVLSQIY-IRDQPDIETEKSFESIEK 406
            .|       ||....  .:.|.|.||:.||:...|. |..:::.|: .||....|.::.....:.
Zfish   359 STSGKIARMCWITDLFIQYIVNIGFYSLVFIFTTII-FIIIVTNIFQSRDIRATEGKRLMFRKQL 422

  Fly   407 NRFKSFWKYFGYTAVVWVVCICSFAFNYYWENRSHLNYAVSFCMAFHGF 455
            ....|.:..||.|   |.|     ||..|........|..|...:|.||
Zfish   423 MMVLSLFLLFGLT---WAV-----AFFSYGPMLIPSYYIFSVLNSFQGF 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl8	NP_611998.1	Methuselah_N	30..202	CDD:429053	4/10 (40%)
		7tm_GPCRs	213..475	CDD:475119	60/266 (23%)
		TM helix 1	214..238	CDD:410628	3/26 (12%)
		TM helix 2	248..269	CDD:410628	3/21 (14%)
		TM helix 5	360..383	CDD:410628	8/22 (36%)
		TM helix 6	409..431	CDD:410628	6/21 (29%)
		TM helix 7	434..465	CDD:410628	6/22 (27%)
LOC103911493	XP_068073930.2	None