Protein Alignment mthl8 and adgre15

DIOPT Version :10

• Sequence 1: NP_611998.1
• Gene: mthl8 / 38013
• FlyBaseID: FBgn0052475
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_021333205.2
• Gene: adgre15 / 100536619
• ZFINID: ZDB-GENE-121214-33
• Length: 857
• Species: Danio rerio
• Alignment Length: 251
• Identity: 53/251 - (21%)
• Similarity: 86/251 - (34%)
• Gaps: 94/251 - (37%)

  Fly   196 EWQP---LACAPEKLYFVLGVREW------------TYAICLLIAILSMFIVLM----------- 234
            |::|   |:|    :|:  .:.||            ::.:|..:. ||.|.::|
Zfish   528 EFEPSGSLSC----VYW--NISEWIVDGCSVLNSNSSHTVCSCVH-LSTFALIMQTSSSPPPSDL 585

  Fly   235 ---VYLMCSEMRNSFYGVAIKAYAICM----------------ILGYALL-----AYLTLHNPAN 275
               :.|:|..:...|:.:|:.::|:|.                :|...||     .:|:|..|..
Zfish   586 LELLGLVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQ 650

  Fly   276 -LSNAACRILPSLALMNLVLSFY--ILSFIAFK------------LYLSFYGVVFTKLMFWLIFT 325
             |..|...:|..|.|...|..|.  :|.||..|            |...|..|:...|...::..
Zfish   651 VLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVCV 715

  Fly   326 PIVLVAVGWSFFVGFSYYGSRLIFGGDTCWFDPRN---WSVMIYFYAPVFVACAIS 378
            .|.||..|               :|.:.||.....   ||    |..||.|..|::
Zfish   716 SIGLVPEG---------------YGSEHCWIKTDEGFIWS----FLGPVCVILALN 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl8	NP_611998.1	Methuselah_N	30..202	CDD:429053	3/8 (38%)
		7tm_GPCRs	213..475	CDD:475119	48/231 (21%)
		TM helix 1	214..238	CDD:410628	7/49 (14%)
		TM helix 2	248..269	CDD:410628	6/41 (15%)
		TM helix 5	360..383	CDD:410628	7/22 (32%)
		TM helix 6	409..431	CDD:410628
		TM helix 7	434..465	CDD:410628
adgre15	XP_021333205.2	None