DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kr and CMR3

DIOPT Version :9

Sequence 1:	NP_001261181.1	Gene:	Kr / 38012	FlyBaseID:	FBgn0001325	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_015338.1	Gene:	CMR3 / 856123	SGDID:	S000006217	Length:	317	Species:	Saccharomyces cerevisiae

Alignment Length:	204	Identity:	53/204 - (25%)
Similarity:	83/204 - (40%)	Gaps:	38/204 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 AQQSLPPQGTHLHSPPASPHSPLSTP--LGSGKHPLNSPNSTPQHHEPAKKARKLSVKKEFQTEI 172
            :||.:|    |..||..:..:||..|  :.:...||     ||...||...|.:.:.     |.|
Yeast   136 SQQPIP----HSQSPHLTSSAPLMMPVMVPTVYKPL-----TPYDKEPITIASEPNF-----TAI 186

  Fly   173 SMSVN-----DMYHTSGGPISPPSSGSSPNSTHDGAGGNAGCVGVSKDPSRDKSFTCKICSRSFG 232
            ||:.:     ::.|.....: ||..|..|.......|             |.||....:.:.|..
Yeast   187 SMASHPNAALELCHDRPKSV-PPGYGVLPTMQEASNG-------------RTKSEPGAVLNGSAT 237

  Fly   233 YKHVLQNHERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCS--HCDRQFVQVANLRR 295
            :.. .:...|..:.:...:||.|.|..:|...||||..:|||:.|:.|:  .|.:.|...:|:.|
Yeast   238 FSD-WKTDTRISSTKLRKQCPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLR 301

  Fly   296 HLRVHTGER 304
            ||:.|..:|
Yeast   302 HLKSHERKR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr	NP_001261181.1	C2H2 Zn finger	224..244	CDD:275368	2/19 (11%)
		zf-H2C2_2	237..261	CDD:290200	5/23 (22%)
		C2H2 Zn finger	252..272	CDD:275368	9/19 (47%)
		zf-H2C2_2	264..289	CDD:290200	11/26 (42%)
		C2H2 Zn finger	280..300	CDD:275368	7/21 (33%)
		zf-H2C2_2	292..316	CDD:290200	6/13 (46%)
		C2H2 Zn finger	308..328	CDD:275368
		zf-H2C2_2	321..345	CDD:290200
		C2H2 Zn finger	336..352	CDD:275368
CMR3	NP_015338.1	COG5048	17..316	CDD:227381	53/204 (26%)
		C2H2 Zn finger	256..276	CDD:275370	9/19 (47%)
		C2H2 Zn finger	284..306	CDD:275370	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050